~29 spots leftby Dec 2025

Conversation Therapy for Aphasia

Recruiting in Palo Alto (17 mi)
+2 other locations
EH
GD
Overseen byGayle DeDe, PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Boston University Charles River Campus
No Placebo Group
Approved in 3 Jurisdictions

Trial Summary

What is the purpose of this trial?

The proposed research will test the efficacy of group conversation treatment for people with aphasia and explore whether the effects of treatment differ as a result of the following factors: 1. Group size: Do large groups of 6-8 people with aphasia or dyads of 2 people with aphasia demonstrate different levels of improvement with this treatment? 2. Group composition: Do effects of conversation group treatment differ if the groups include members with similar or different types of aphasia? 3. Aphasia severity: Do effects of conversation group treatment differ if the individuals within the group have mild-moderate or moderate-severe profiles of aphasia? Treatment sessions will occur in groups of 6-8 people with aphasia or with 2 people with aphasia. During treatment sessions, discourse will be facilitated on a focused set of every day topics, such as current events or travel. Linguistic and multi modal cueing hierarchies will be tailored to individual client goals and used to maximize communication success. The prediction is that conversation treatment is an effective method for improving communication in people with aphasia, but that specific benefits may differ based on variables such as group size, group composition, and aphasia severity. The results will help inform best practices for aphasia treatment and refine a hypothesized model about the mechanisms underlying conversation treatment.

Do I have to stop taking my current medications for the trial?

The trial protocol does not specify whether you need to stop taking your current medications. However, you must abstain from any concurrent speech language treatment.

What data supports the idea that Conversation Therapy for Aphasia is an effective treatment?

The available research shows that Conversation Therapy for Aphasia is effective in improving communication skills. One study found that participants who received group communication treatment had significantly higher scores on communication and language tests compared to those who did not receive the treatment. Improvements were seen after just two months and continued after four months of treatment, with no decline in performance after stopping the treatment. Another study compared individual and group treatments and found that both methods led to significant improvements in language abilities, suggesting that group therapy is a viable option for managing aphasia.12345

What safety data exists for conversation therapy for aphasia?

The provided research does not specifically address safety data for conversation therapy for aphasia. The studies focus on the efficacy, mechanisms of change, and outcomes of the therapy, such as improvements in communication, language impairment, and quality of life. However, there is no mention of adverse effects or safety concerns, suggesting that the therapy is generally considered safe, but specific safety data is not detailed in these abstracts.25678

Is Conversation Treatment for Aphasia a promising treatment?

Yes, Conversation Treatment for Aphasia is promising because it can improve communication skills and reduce social isolation for people with aphasia. It also helps them practice communication in a group setting, which can boost their confidence and help them connect with others.24569

Research Team

EH

Elizabeth Hoover, PhD

Principal Investigator

Boston University

GD

Gayle DeDe, PhD

Principal Investigator

Temple University

Eligibility Criteria

This trial is for English-speaking adults with aphasia, a language disorder typically caused by stroke. They must be at least 6 months post-stroke and have enough understanding to join in conversations. The study includes all severity levels of aphasia but excludes those with other neurological diseases, developmental disabilities, or serious illnesses like cancer.

Inclusion Criteria

I have been diagnosed with difficulty in speaking or understanding language.
You need to be able to understand and take part in conversations, as shown by standardized tests for language difficulties.
I have severe difficulty speaking or understanding speech.
See 4 more

Exclusion Criteria

I have not had any neurological diseases, except for a stroke.
Participants will be asked to abstain from concurrent speech language treatment
I do not have any serious illnesses right now.
See 1 more

Treatment Details

Interventions

  • Conversation Treatment for Aphasia (Behavioral Intervention)
Trial OverviewThe study tests group conversation treatment's effectiveness on communication skills in people with aphasia. It examines how different group sizes (2 vs. 6-8 people) and compositions (similar vs. different types of aphasia), as well as the severity of aphasia, impact the treatment outcome.
Participant Groups
3Treatment groups
Experimental Treatment
Active Control
Group I: Experimental: Group compositionExperimental Treatment1 Intervention
Outcomes will be measured for individuals who participate in homogeneous compared to heterogeneous groups (6-8 people with aphasia), based on aphasia severity (severe vs. mild-moderate aphasia).
Group II: Experimental: Group Size x Aphasia SeverityExperimental Treatment1 Intervention
Outcomes will be measured for individuals who participate in large group (6-8 group members) compared to dyads (2 group members), and whether this relationship differs as a function of aphasia severity (severe vs. mild-moderate aphasia).
Group III: Treatment efficacy: Delayed Control GroupActive Control1 Intervention
Treatment cycle 1 only.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Temple UniversityPhiladelphia, PA
Boston University - Charles River CampusBoston, MA
Adler Aphasia CenterMaywood, NJ
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Who Is Running the Clinical Trial?

Boston University Charles River Campus

Lead Sponsor

Trials
125
Patients Recruited
14,100+

Temple University

Collaborator

Trials
321
Patients Recruited
89,100+

Adler Aphasia Center

Collaborator

Trials
1
Patients Recruited
160+

Findings from Research

The efficacy of group communication treatment in adults with chronic aphasia.Elman, RJ., Bernstein-Ellis, E.[2022]
Identifying mechanisms of change in a conversation therapy for aphasia using behaviour change theory and qualitative methods.Johnson, FM., Best, W., Beckley, FC., et al.[2019]
Veterans Administration cooperative study on aphasia: a comparison of individual and group treatment.Wertz, RT., Collins, MJ., Weiss, D., et al.[2019]
An Exploration of the Impact of Group Treatment for Aphasia on Connected Speech.Mason, C., Nickels, L., McDonald, B.[2021]
A Randomized Controlled Trial of the Effects of Group Conversation Treatment on Monologic Discourse in Aphasia.Hoover, E., DeDe, G., Maas, E.[2023]
Conversation therapy for aphasia: a qualitative review of the literature.Simmons-Mackie, N., Savage, MC., Worrall, L.[2022]
Efficacy of Aphasia Group Conversation Treatment via Telepractice on Language and Patient-Reported Outcome Measures.Dunne, M., Hoover, E., DeDe, G.[2023]
Two to Tango or the More the Merrier? A Randomized Controlled Trial of the Effects of Group Size in Aphasia Conversation Treatment on Standardized Tests.DeDe, G., Hoover, E., Maas, E.[2020]
A sociolinguistic analysis of group therapy for aphasia involving eight adults showed that therapy can effectively enhance both communication skills and personal identity through supportive discourse.
Key elements of successful identity negotiation in therapy included ensuring group members felt 'heard', promoting their competence, fostering group solidarity, and managing interactions to support positive personal identities.
Negotiation of identity in group therapy for aphasia: the Aphasia Café.Simmons-Mackie, N., Elman, RJ.[2016]

References

The efficacy of group communication treatment in adults with chronic aphasia. [2022]
Identifying mechanisms of change in a conversation therapy for aphasia using behaviour change theory and qualitative methods. [2019]
Veterans Administration cooperative study on aphasia: a comparison of individual and group treatment. [2019]
An Exploration of the Impact of Group Treatment for Aphasia on Connected Speech. [2021]
A Randomized Controlled Trial of the Effects of Group Conversation Treatment on Monologic Discourse in Aphasia. [2023]
Conversation therapy for aphasia: a qualitative review of the literature. [2022]
Efficacy of Aphasia Group Conversation Treatment via Telepractice on Language and Patient-Reported Outcome Measures. [2023]
Two to Tango or the More the Merrier? A Randomized Controlled Trial of the Effects of Group Size in Aphasia Conversation Treatment on Standardized Tests. [2020]
Negotiation of identity in group therapy for aphasia: the Aphasia Café. [2016]