~60 spots leftby Aug 2028

Naming Treatment for Aphasia

Recruiting in Palo Alto (17 mi)
Overseen byErica L Middleton, PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Albert Einstein Healthcare Network
No Placebo Group

Trial Summary

What is the purpose of this trial?Aphasia is a disorder of spoken and written language, most commonly following a stroke. It is estimated that between 2.5 and 4 million Americans are living with aphasia today. A common problem in aphasia involves difficulty retrieving known words in the course of language production and comprehension. The overarching goal of this project is to develop and test early efficacy, efficiency, and the tolerability of a lexical treatment for aphasia in multiple-session regimens that are comprised of retrieval practice, distributed practice, and training dedicated to the elicitation of correct retrievals. The aim of this work is to add to and refine the evidence base for the implementation and optimization of these elements in the treatment of production and comprehension deficits in aphasia, and make important steps towards an ultimate goal of self-administered lexical treatment grounded in retrieval practice principles (RPP) to supplement traditional speech-language therapy that is appropriate for People with Aphasia (PWA) from a broad level of severity of lexical processing deficit in naming and/or comprehension. This project cumulatively builds on prior work to develop a theory of learning for lexical processing impairment in aphasia that aims to ultimately explain why and for whom familiar lexical treatments work, and how to maximize the benefits they confer.

Eligibility Criteria

This trial is for adults who have had a stroke at least 6 months ago and primarily speak English. It's designed to help those with aphasia, which is a language disorder affecting speech and comprehension.

Inclusion Criteria

English is my first language.
I had a stroke more than 6 months ago.

Participant Groups

The study tests a treatment called 'Criterion-learning practice' aimed at improving word retrieval in people with aphasia. The treatment involves exercises that focus on correct word usage, spread out over multiple sessions.
1Treatment groups
Experimental Treatment
Group I: Criterion-learning practiceExperimental Treatment1 Intervention
This is a single-arm study.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Moss Rehabilitation Research InstituteElkins Park, PA
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Who Is Running the Clinical Trial?

Albert Einstein Healthcare NetworkLead Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)Collaborator
Thomas Jefferson UniversityCollaborator

References