~4 spots leftby Jun 2025

Technology & Exercise Programming for Osteoarthritis

(TEAM Trial)

Recruiting in Palo Alto (17 mi)
JT
Overseen byJane Thornton, MD PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Western University, Canada
No Placebo Group

Trial Summary

What is the purpose of this trial?

Many individuals with osteoarthritis (OA) (up to 45%) are referred to an orthopaedic surgeon for a joint replacement prematurely or will not be candidates for surgery. These individuals need appropriate (non-operative) care to help reduce their pain and enhance their mobility. We are studying the use of innovative technology to help physicians give physical activity advice for patients to become more active and provide free online resources to help patients understand OA self-management and exercise, especially when they have barriers to accessing formal care. Individuals with OA that are referred to a specialized clinic will receive one of three interventions: usual care (handout on resources), a physical activity prescription by a doctor, or the prescription and a link to a free web-based platform (website) on non-operative management of OA with patient education and exercise videos. Our goal is to help with non-operative management strategies to improve quality of life, reduce pain, improve mobility, and possibly delay or prevent a joint replacement. Osteoarthritis is a condition where people feel joint pain or stiffness. Joints are the body parts where two bones join together with softer material (cartilage) between them. In osteoarthritis, this cartilage wears down. It is the biggest cause for disability worldwide. Helping people with osteoarthritis starts with education, physical activity, and physiotherapy. Doctors can also prescribe braces, injections or medications. For severe osteoarthritis when nothing else helps, surgery can be done to replace the joint. Doctors often refer patients for surgery too soon. Skipping steps of care may mean unnecessary surgery and longer wait times. The Musculoskeletal Rapid Access Clinic (now called Clinic) in London was set up to solve these problems. They screen patients before referring them to a surgeon, and do not refer almost half of patients. Our goal is to support these patients with new ways to make their non-surgical treatment better. The first way is through physical activity 'prescription'. It works well for other chronic conditions and patients say it helps. We don't know how well it works for people with osteoarthritis. Most doctors have little time, training or experience for prescribing physical activity. Technology can make it easier for doctors and patients. We have designed a tool to help doctors prescribe physical activity and a smartphone app to track patient activity. We have also created a free website. This includes patient education, exercise videos, and virtual physiotherapy. This can be important for individuals who can't access in-person care.

Research Team

JT

Jane Thornton, MD PhD

Principal Investigator

Western University

Eligibility Criteria

This study is for people aged 40-74 with mild to moderate osteoarthritis, as determined by a specialized clinic. Participants must be able to follow the study plan and have internet access. It's not for those awaiting or who've had joint replacement surgery, have inflammatory arthritis, unstable medical conditions like uncontrolled diabetes, or can't communicate in English.

Inclusion Criteria

40-74 years of age
Screened by the Southwest Musculoskeletal RAC as "mild to moderate OA" using clinical and radiographic criteria

Exclusion Criteria

Unstable medical conditions that would preclude physical activity prescription (e.g. unstable angina, uncontrolled Type 2 Diabetes)
Cannot communicate in English.
Concomitant end-stage OA (awaiting/prior TJA)
See 3 more

Treatment Details

Interventions

  • Technology, Exercise Programming, and Activity Prescription for Enhanced Mobility (TEAM) Study (Behavioural Intervention)
Trial OverviewThe TEAM Study tests how technology and doctor-prescribed physical activity can help manage osteoarthritis without surgery. Patients will either get usual care resources, a physical activity prescription from their doctor, or both the prescription and access to an educational website with exercise videos.
Participant Groups
3Treatment groups
Experimental Treatment
Active Control
Group I: PAARx and JMExperimental Treatment2 Interventions
Patients will be prescribed technology-based physical activity programming and be referred to a web-based resource for evidence-based joint management.
Group II: PAARxExperimental Treatment1 Intervention
Patients will be prescribed technology-based physical activity programming.
Group III: Usual CareActive Control1 Intervention
Patients will receive the usual care.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Western University, Canada

Lead Sponsor

Trials
270
Recruited
62,500+
Dr. Robin Farias-Eisner profile image

Dr. Robin Farias-Eisner

Western University, Canada

Chief Executive Officer since 2022

PhD in Molecular Biology from UCLA, MD from the Royal College of Surgeons in Dublin, MBA from Pepperdine University

James Tweedy profile image

James Tweedy

Western University, Canada

Chief Medical Officer since 2020

MBA from Trinity Western University