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Behavioral Intervention

ALDER Program for Anxiety Disorders (ALDER Trial)

N/A
Waitlist Available
Led By Elizabeth Addington, PhD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 65 and over.
BZRA prescribed by NM primary care within the past year.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured at baseline (pre-intervention).
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to test an online program called ALDER in patients over 65 who are taking benzodiazepine medications. The trial wants to see if ALDER can help increase positive emotions,

Who is the study for?
This trial is for individuals over the age of 65 who use benzodiazepines at least twice a week, have had a clinic visit within the past year, and can access the internet daily. They must be able to read and speak English and have their medication prescribed by NM primary care in the last year.
What is being tested?
The ALDER program, an online self-guided intervention aimed at increasing positive emotions and reducing anxiety, sleep issues, and dependence on benzodiazepine medications among older adults is being tested.
What are the potential side effects?
Since ALDER is a non-medical intervention focusing on emotion regulation through online activities, it may not have direct side effects like medications do. However, participants might experience emotional discomfort or fatigue.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 65 years old or older.
Select...
I was prescribed a benzodiazepine by my primary care doctor in the last year.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured post-intervention (7-weeks).
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured post-intervention (7-weeks). for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Acceptability of intervention
Adoption of intervention
Feasibility of intervention
Secondary study objectives
Patient attitude towards deprescribing BZRAs
Patient benzodiazepine receptor agonist (BZRA) use
Patient-reported anxiety
+6 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: InterventionExperimental Treatment1 Intervention
Participants will go through a 5-week online self-guided positive emotion skills course.

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Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,634 Previous Clinical Trials
957,169 Total Patients Enrolled
Elizabeth Addington, PhDPrincipal InvestigatorNorthwestern University
1 Previous Clinical Trials
21 Total Patients Enrolled
~27 spots leftby Oct 2025
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