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Cannabis Use and Perception (PISCES Trial)

N/A
Waitlist Available
Research Sponsored by University of Colorado, Boulder
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
21-65 years of age
At least occasional use of CBD+THC or CBD-dominant products (e.g., ≥1x/month)
Must not have
Females cannot be pregnant or trying to become pregnant or nursing mothers
Not able to provide informed consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up pre-use/pre-water task, pre-use/post-water task, 20 minutes post-use, 40 minutes post-use

Summary

This trial aims to study how cannabis affects mental and physical states like mood, cognition, perception, and heart rate. Participants will be in the study for about a week, spending 2.5 hours

Who is the study for?
This study is for individuals who use cannabis, with or without a history of cannabis abuse, and are interested in how it affects their mood, thinking, perception of temperature and pain, as well as heart rate. Participants will be involved for about one week.
What is being tested?
The trial is exploring the impact of smoking cannabis on mental and physical responses by varying water temperatures (CW and WW) during tests. It involves two visits over a week totaling around 2.5 hours to complete the tasks.
What are the potential side effects?
Since this study focuses on perceptions after using cannabis rather than a drug intervention, side effects may include altered mood states, changes in cognitive function or perception issues related to temperature and pain.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 21 and 65 years old.
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I use CBD+THC or CBD products at least once a month.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am not pregnant, trying to conceive, or breastfeeding.
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I am unable to understand or sign the consent form.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediate post-use
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediate post-use for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Blood Cortisol Levels
Blood Endocannabinoid Levels
Blood cannabinoid levels
+7 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Cold WaterExperimental Treatment1 Intervention
Group II: Warm WaterPlacebo Group1 Intervention

Find a Location

Who is running the clinical trial?

University of Colorado, BoulderLead Sponsor
124 Previous Clinical Trials
29,399 Total Patients Enrolled
National Institute on Drug Abuse (NIDA)NIH
2,594 Previous Clinical Trials
3,328,570 Total Patients Enrolled
~111 spots leftby Jul 2029
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