SBRT for Non-Small Cell Lung Cancer

Recruiting in Palo Alto (17 mi)

Overseen byAnurag Singh, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Roswell Park Cancer Institute

No Placebo Group

Approved in 4 Jurisdictions

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine if a single treatment of targeted radiation (called SBRT or Stereotactic Body Radiation Therapy) can be as safe and effective as multiple doses of radiation in patients with central non-small cell lung cancer

Research Team

Anurag Singh, MD

Principal Investigator

Roswell Park Comprehensive Cancer Center

Eligibility Criteria

This trial is for adults with a confirmed diagnosis of central non-small cell lung cancer (NSCLC) that's in an early stage and smaller than 6 cm. They should be unable to have or refuse surgery, not pregnant, and haven't had recent chemotherapy or radiation. Participants must understand the study's experimental nature and agree to use birth control if they can have children.

Inclusion Criteria

I cannot or choose not to have surgery for my condition.

Participants of child-bearing potential must agree to use adequate contraceptive methods (e.g., hormonal or barrier method of birth control; abstinence) prior to study entry.

I am able to get out of my bed or chair and move around.

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Exclusion Criteria

I do not have any severe illnesses or social situations that would stop me from following the study's requirements.

I do not have brain metastases.

I haven't had chemotherapy or radiotherapy in the last 4 weeks, or I've recovered from its side effects.

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Treatment Details

Interventions

SBRT (Radiation Therapy)

Trial OverviewThe study tests whether one session of targeted radiation therapy (SBRT) is as effective and safe as multiple sessions for treating central NSCLC. It aims to see if this single treatment can help patients who are not candidates for surgery.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Stereotactic Body Radiation Therapy (SBRT)Experimental Treatment1 Intervention

A single fraction of targeted SBRT

SBRT is already approved in United States, European Union, Canada, Japan for the following indications:

🇺🇸 Approved in United States as SBRT for: