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Nasal High Flow for COPD

N/A
Waitlist Available
Led By Saramaria Afanador Castiblanco, M.D.
Research Sponsored by University of Miami
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18 years or older
Diagnosis of COPD
Must not have
Being on bedrest
Inability to consent or cooperate with the study
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 minutes
Awards & highlights

Summary

This trial will see if using a high flow of oxygen through the nose during a walking test helps COPD patients. The study will focus on how this treatment impacts the patients' ability to walk and their

Who is the study for?
This trial is for individuals with Chronic Obstructive Pulmonary Disease (COPD) who are able to perform a 6-Minute Walk Test (6-MWT). Specific eligibility criteria details were not provided, so it's important to contact the study organizers for more information on who can participate.
What is being tested?
The study is testing the effects of two types of oxygen delivery during exercise: high flow nasal cannula at 70 liters per minute and low flow. It measures how these affect exercise tolerance and breathlessness in COPD patients after walking for six minutes.
What are the potential side effects?
Potential side effects were not detailed, but using different flows of nasal cannula may cause varying levels of comfort or dryness in the nose, throat discomfort, or could impact breathing during exertion.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am 18 years old or older.
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I have been diagnosed with COPD.
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I use a low-flow nasal cannula at 4L/min or less, or I don't use supplemental oxygen.
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I can walk on my own without help.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am currently on bedrest.
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I am unable to understand or follow the study's requirements.
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I need more than 4 liters per minute of oxygen or use a non-invasive ventilator during the day.
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My heart rate and blood pressure are stable.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 minutes for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
6-minute walk test
Secondary study objectives
Breathing measured by the Borg dyspnea scale

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Nasal High Flow CannulaExperimental Treatment2 Interventions
Nasal High Flow cannula at 70 liters per minute for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to Nasal Low Flow Cannula at less than or equal to 4 liters per minute with supplemental oxygen for 30 minutes
Group II: Nasal Low Flow CannulaActive Control2 Interventions
Low Flow Nasal Cannula at less than or equal to 4 liters per minute with supplemental oxygen at patient's baseline for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to High Flow Cannula at 70 liters per minute for 30 minutes

Find a Location

Who is running the clinical trial?

University of MiamiLead Sponsor
935 Previous Clinical Trials
422,187 Total Patients Enrolled
American Thoracic SocietyOTHER
10 Previous Clinical Trials
639 Total Patients Enrolled
Saramaria Afanador Castiblanco, M.D.Principal InvestigatorUniversity of Miami
~20 spots leftby Dec 2027
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