Radiation Therapy
Stereotactic Radiosurgery for Spinal Cord Compression
This trial is testing a one-time high-dose radiation treatment called Spine Stereotactic Radiosurgery (SSRS) for patients with spinal cord compression from cancer who can't have surgery. The goal is to see if this precise treatment can stop tumor growth and prevent spinal cord injury. Patients will be monitored regularly to check their progress. Spine stereotactic radiosurgery (SSRS) is increasingly being used to treat metastatic spinal tumors and has shown high rates of local tumor control.
Radiation Therapy
Radiosurgery for Trigeminal Neuralgia
This trial is testing a new type of non-invasive surgery that uses precise radiation to treat severe facial pain. It targets patients with trigeminal neuralgia who may not respond to other treatments. The goal is to see if this method can effectively reduce or stop their pain.
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Trials for Adenocarcinoma Patients
Radiation Therapy
Stereotactic Radiotherapy for Lung Cancer
This trial is testing SBRT, a precise radiation treatment for lung tumors. It targets tumors with high doses from multiple angles to shrink them and control cancer growth. The treatment is aimed at patients with lung cancer and metastases. SBRT, also known as stereotactic ablative radiotherapy (SABR), is a precise radiation treatment developed originally for intracranial targets and now widely used for treating lung tumors and metastases.
Radiation
CAN-2409 + Chemoradiation/SBRT for Pancreatic Cancer
This trial is testing a new immunotherapy treatment for pancreatic cancer that has shown promise in earlier trials. The new treatment will be given in combination with standard chemotherapy and radiation, and the goal is to see if it improves outcomes for patients with pancreatic cancer.
Trials for NSCLC Patients
Radiation Therapy
Stereotactic Radiotherapy for Lung Cancer
This trial is testing SBRT, a precise radiation treatment for lung tumors. It targets tumors with high doses from multiple angles to shrink them and control cancer growth. The treatment is aimed at patients with lung cancer and metastases. SBRT, also known as stereotactic ablative radiotherapy (SABR), is a precise radiation treatment developed originally for intracranial targets and now widely used for treating lung tumors and metastases.
Monoclonal Antibodies
Durvalumab + SBRT for Non-Small Cell Lung Cancer
This trial is testing a combination of two treatments, Durvalumab and stereotactic body radiation therapy (SBRT), to see if it is more effective in fighting lung cancer than Durvalumab alone.
Radiation
Stereotactic Ablative Radiosurgery for Lung Cancer
This trial is for patients with early stage lung cancer or a single pulmonary metastasis. Three tumor locator beacons are placed in the small bronchial airways near the tumors. This allows for smaller treatment volumes of Stereotactic Ablative Radiosurgery (SABR) and more precise delivery of radiotherapy.
Radiation Therapy
SBRT for Non-Small Cell Lung Cancer
This trial tests different levels of radiation to find the safest high dose for patients with high-risk ultracentral tumors. It uses a method that adjusts doses based on patient responses to minimize severe side effects.
Phase 3 Trials
Radiation Therapy
Radiosurgery vs Whole Brain Radiation for Brain Metastasis
This trial compares two radiation treatments for brain tumors from non-melanoma cancers. One treatment is a focused, high-dose method, while the other treats the entire brain over several sessions. The goal is to determine which method controls tumors better and has fewer side effects on thinking and memory. The focused, high-dose method has been increasingly used over the past years as an effective treatment for brain metastases, often replacing the whole brain treatment due to its ability to improve outcomes and reduce side effects.
Radiation
Stereotactic Radiosurgery vs. HA-WBRT + Memantine for Brain Cancer
This trial is testing whether memantine used in combination with HA-WBRT helps to improve mental function (measured by how well patients can remember things) compared to those who receive HA-WBRT alone.
Trials With No Placebo
Radiation Therapy
Stereotactic Radiosurgery for Brain Tumors
This trial aims to study the side effects and determine the optimal dose of a type of radiation therapy called stereotactic radiosurgery for treating patients with large brain metastases. Radiosurgery targets the tumor
Radiation Therapy
Stereotactic Radiotherapy for Lung Cancer
This trial is testing SBRT, a precise radiation treatment for lung tumors. It targets tumors with high doses from multiple angles to shrink them and control cancer growth. The treatment is aimed at patients with lung cancer and metastases. SBRT, also known as stereotactic ablative radiotherapy (SABR), is a precise radiation treatment developed originally for intracranial targets and now widely used for treating lung tumors and metastases.
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Frequently Asked Questions
Introduction to sbrt
What are the top hospitals conducting sbrt research?
Cutting-edge advancements in the field of radiation therapy are being pioneered by top hospitals across the globe, with a particular focus on Stereotactic Body Radiation Therapy (SBRT). Hospitals such as M D Anderson Cancer Center in Houston are leading the way with six active SBRT trials. Notably, this center has embarked on groundbreaking research to enhance treatment options for patients using SBRT. In Boston, Beth Israel Deaconess Medical Center is also making significant strides, currently conducting four active SBRT trials. The collaboration between researchers and physicians at this esteemed institution aims to revolutionize cancer care through innovative approaches utilizing SBRT technology.
Venturing northward to Edmonton's Cross Cancer Institute reveals another hub of pioneering medical research. With four ongoing clinical trials centered around SBRT, this Canadian institute plays a vital role in advancing knowledge and improving outcomes for patients undergoing radiotherapy treatments. Similarly focused on innovation is Emory University Hospital/Winship Cancer Institute in Atlanta where an equal number of active SBRT trials are underway. By exploring the potential of this cutting-edge technology, these institutions aim to optimize radiation therapy protocols and ultimately improve patient survival rates.
Situated in Hamilton, Canada's Juravinski Cancer Centre completes our list of top hospitals involved in current SBRT trials. This dynamic facility is actively engaged in three clinical studies that harness the power of precise radiation delivery techniques offered by SBRT. Through their commitment to advancing scientific understanding and patient care within oncology treatments like SBRT, these hospitals contribute significantly towards better outcomes for individuals facing various forms of cancer requiring radiation intervention.
Collectively, these world-class medical institutions showcase their unwavering dedication to finding innovative solutions that challenge conventional practices while aiming for improved therapeutic success rates with minimally invasive procedures.
Which are the best cities for sbrt clinical trials?
When it comes to sbrt clinical trials, several cities stand out as hubs of research and development. New york, New York leads the way with 20 active trials exploring treatments like Fractionated Stereotactic Radiosurgery and Pembrolizumab combined with SRS. Boston, Massachusetts closely follows with 19 ongoing studies focused on interventions such as FOLFIRINOX and AGuIX. Houston, Texas is also a notable location with 14 active trials investigating treatments like Stereotactic Radiosurgery and the NovoTTF-200M device. Lastly, Montréal, Quebec offers promising opportunities with 13 active trials studying SBRT and other potential breakthroughs. These cities provide access to cutting-edge sbrt clinical trials that drive innovation in care for patients seeking advanced treatment options.
Which are the top treatments for sbrt being explored in clinical trials?
Stereotactic body radiation therapy (SBRT) is an area of active research, with several promising treatments currently being explored in clinical trials. Among the top contenders are:
- Daratumumab: Being tested in 6 ongoing SBRT trials
- Belantamab mafodotin: Under investigation in 4 active SBRT studies
- Lenalidomide: Currently involved in 3 clinical trials focused on SBRT.
What are the most recent clinical trials for sbrt?
The field of Stereotactic Body Radiation Therapy (SBRT) is witnessing promising advancements through recent clinical trials. One such study focuses on men with low to intermediate risk prostate cancer, evaluating the effectiveness of SBRT as a treatment option. Another trial investigates the application of radiosurgery in SBRT, seeking to determine its potential benefits across different phases. Additionally, cisplatin has emerged as a candidate for use alongside SBRT, offering new possibilities for patient care. Notably, standard dose SBRT and olaparib have also been explored in separate Phase 2 trials, presenting alternative avenues for optimizing treatment outcomes. These ongoing studies hold promise for refining and expanding the role of SBRT in various medical contexts.
What sbrt clinical trials were recently completed?
Recently completed clinical trials in the field of Stereotactic Body Radiation Therapy (SBRT) have made significant contributions to advancing cancer treatment. Notably, a trial investigating the efficacy and safety of SBRT for lung cancer was successfully completed, providing valuable insights into this innovative therapy. The completion of this groundbreaking study marks an important milestone in improving outcomes for patients undergoing radiation therapy for lung cancer.