Trial Summary
What is the purpose of this trial?
Emerging studies in humans found that 40 Hz sound induces neural gamma oscillation and enhanced cognitive function in older adults with and without Alzheimer's Disease. We will compare a 40 Hz music intervention to both 40 Hz sound and music alone in a clinical cohort of older adults with mild cognitive impairment.
Eligibility Criteria
This trial is for older adults who have mild cognitive impairment but can still take care of themselves. They shouldn't have dementia, schizophrenia, Parkinson's disease, severe hearing loss, or any serious medical/psychiatric issues that would stop them from following the study.Inclusion Criteria
I live at home and have memory loss or mild thinking problems.
My organs are working well.
No dementia
Exclusion Criteria
I have been diagnosed with schizophrenia or Parkinson's disease.
I have severe hearing loss.
Presence of an acute medical or psychiatric condition which would interfere with the subject's ability to follow the study protocol realistically
Treatment Details
Interventions
- 40 Hz music (Sound Therapy)
- 40 Hz sound (Sound Therapy)
- Preferred music (Behavioural Intervention)
Trial OverviewThe study tests three things: music at a specific frequency (40 Hz), just the sound at this frequency without music, and whatever music the participant likes best. The goal is to see if these sounds improve brain function in those with mild cognitive issues.
Participant Groups
3Treatment groups
Experimental Treatment
Group I: 3Experimental Treatment3 Interventions
this group will be exposed to condition C first, then A, and B
Group II: 2Experimental Treatment3 Interventions
this group will be exposed to condition B first, then C, and A
Group III: 1Experimental Treatment3 Interventions
this group will be exposed to condition A first, then B, and C
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Johns Hopkins School of NursingBaltimore, MD
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Who Is Running the Clinical Trial?
Johns Hopkins UniversityLead Sponsor
National Institute on Aging (NIA)Collaborator