← Back to Search

Neuromodulation

Neuromodulation for Hoarding Disorder and Depression

N/A
Recruiting
Led By Elizabeth Twamley, PhD
Research Sponsored by University of California, San Diego
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline to 8 weeks
Awards & highlights

Study Summary

This trial will evaluate if iTBS can effectively treat depression in people with HD, and how it can potentially improve HD symptoms, cognitive performance, and brain region connectivity.

Who is the study for?
This trial is for adults aged 18-70 with both depression and hoarding disorder, who have been stable on psychiatric meds for 6 weeks. They must be able to commit to the treatment schedule, complete assessments in English, and not have any MRI or TMS contraindications. Pregnant individuals or those with certain neurological conditions or high suicide risk are excluded.Check my eligibility
What is being tested?
The study tests intermittent theta burst stimulation (iTBS) effectiveness on treating depression in patients also suffering from chronic hoarding disorder. It will assess improvements in hoarding symptoms, cognitive function, and brain connectivity related to the treatment.See study design
What are the potential side effects?
While specific side effects of iTBS aren't listed here, common ones include discomfort at the stimulation site, headache, lightheadedness, and seizures are a rare but serious risk especially if there's a history of seizures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline to 8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline to 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Hamilton Rating Scale for Depression
Savings Inventory -- Revised
Secondary outcome measures
Hoarding Rating Scale
Neuropsychological Global Deficit Score
Patient Health Questionnaire - 9
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: iTBSExperimental Treatment1 Intervention
intermittent Theta Burst Stimulation (a form of transcranial magnetic stimulation) targeting the left dorsolateral prefrontal cortex
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
iTBS
2019
Completed Phase 3
~640

Find a Location

Who is running the clinical trial?

University of California, San DiegoLead Sponsor
1,130 Previous Clinical Trials
1,552,844 Total Patients Enrolled
30 Trials studying Depression
55,647 Patients Enrolled for Depression
Elizabeth Twamley, PhDPrincipal InvestigatorUC San Diego
2 Previous Clinical Trials
136 Total Patients Enrolled
1 Trials studying Depression
72 Patients Enrolled for Depression

Media Library

Depression Research Study Groups: iTBS
Depression Clinical Trial 2023: iTBS Highlights & Side Effects. Trial Name: NCT05985356 — N/A
iTBS (Neuromodulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05985356 — N/A
~0 spots leftby Jun 2024
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top