Sleep and Light Interventions for Menopausal Depression (SALI Trial)

N/A

Waitlist Available

Led By Barbara Parry, M.D.

Research Sponsored by University of California, San Diego

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Above age 18

Experiencing at least moderate depression symptoms (i.e., score of at least 10 on PHQ-9)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion.

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to study how mood, sleep, and activity are affected during menopause and if they can be improved by adjusting sleep timing and exposure to bright light. Participants will provide urine samples to measure

Who is the study for?

This trial is for women experiencing mood and sleep issues during menopause. Participants will need to adjust their sleep schedule for one night, use a light box daily for two weeks, provide urine samples, fill out questionnaires on mood and sleep, and wear an activity tracker.

What is being tested?

Researchers are testing if adjusting the timing of sleep (earlier or later) combined with exposure to bright white light in the morning or evening can improve melatonin levels, mood, and sleep patterns in menopausal women.

What are the potential side effects?

Potential side effects may include discomfort from changing sleep schedules or sitting in front of a light box which could affect eyesight temporarily. Mood changes might also occur due to alterations in circadian rhythms.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am over 18 years old.

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I am experiencing moderate to severe depression.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion.

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and after completing two-week intervention; sustained at two weeks post intervention completion through three months post intervention completion. for reporting.