Trial Summary
What is the purpose of this trial?The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.
Eligibility Criteria
This trial is for people with primary progressive or relapsing and remitting multiple sclerosis who experience dizziness, imbalance, or have had falls. Participants must speak English fluently and not have had recent MS symptom worsening, immunotherapy changes, severe high blood pressure, certain eye conditions like lazy eye or ongoing vestibular rehabilitation.Inclusion Criteria
Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per the 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS
Fluent in speaking and understanding English
I often feel dizzy, have balance issues, and have fallen at least twice in the last year.
Exclusion Criteria
Static visual acuity with correction of worse than 1.0 logMAR
I have had a single neurological event or MRI findings suggestive of MS.
My MS symptoms have gotten worse in the last 60 days.
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Participant Groups
The study tests a new treatment called StableEyes aimed at reducing dizziness in those with multiple sclerosis. It compares daily personalized gaze stabilization training against intermittent training to see which helps more with vestibular symptoms.
2Treatment groups
Experimental Treatment
Group I: Intermittent incremental vestibulo-ocular Reflex Adaptation (I-IVA-GSE)Experimental Treatment1 Intervention
The I-IVA-GSE group will perform two, 15-minute IVA-GSE sessions (30 minutes total), three days per week, with at least one day between each exercise day.
Group II: Daily Incremental Vestibulo-ocular Reflex Adaptation (D-IVA-GSE)Experimental Treatment1 Intervention
The dosages of the D-IVA-GSE and I-IVA-GSE are based on the FITT principle of exercise prescription (frequency, intensity, time, and type). The D-IVA-GSE group will perform two, 15- minute GSE sessions (30-minutes total per day), seven days per week.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Emory UniveristyAtlanta, GA
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Who Is Running the Clinical Trial?
Emory UniversityLead Sponsor
National Multiple Sclerosis SocietyCollaborator