~37 spots leftby Apr 2026

Down Syndrome Clinical Trials - Study of Alzheimer's Disease in Down Syndrome

(LIFE-DSR Trial)

Recruiting in Palo Alto (17 mi)
+14 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: LuMind IDSC Foundation
No Placebo Group

Trial Summary

What is the purpose of this trial?

The primary objective is to characterize trajectories of change on the primary outcome measures in this study population through longitudinal collection of measures of cognition, function, behavior, and health status.

Eligibility Criteria

Inclusion Criteria

Age 25 years or older
Diagnosis of DS, typically supported by karyotype analysis documenting full trisomy for chromosome 21 or complete unbalanced translocation of chromosome 21. Karyotype analysis is not required for study entry
Participants, or Legal Authorized Representative, and their study partner if applicable, in the opinion of the investigator, are able to understand and willing to sign written informed consent.
See 2 more

Treatment Details

Interventions

  • Observational Study (Behavioural Intervention)

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Barrow Neurological InstitutePhoenix, AZ
Advocate HealthPark Ridge, IL
Kansas University Medical CenterFairway, KS
Massachusetts General HospitalBoston, MA
More Trial Locations
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Who Is Running the Clinical Trial?

LuMind IDSC FoundationLead Sponsor
Alzheimer's Disease Cooperative Study (ADCS)Collaborator

References