Trial Summary
What is the purpose of this trial?This interventional trial recruits women with endometrial cancer to participate in high intensity interval training (HIIT) prior to their standard of care surgery. The study will evaluate tissue and blood to determine if HIIT training has anti-cancer effects. P
Eligibility Criteria
Women aged 40-75 with endometrial cancer, scheduled for surgery, and a BMI of 30-50 kg/m2 can join. They must have early-stage disease, access to email and a smartphone, and be able to visit the lab for tests. Those with recent severe cardiovascular events, other interventions or conditions that limit safe participation are excluded.Inclusion Criteria
Your body mass index (BMI) is between 30 and 50, which means you may be overweight or have obesity.
I agree to visit the lab for baseline testing within 2 days if it can't be done the same day as my standard of care visit.
I have access to email.
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Exclusion Criteria
I have severe hearing or speech impairments.
You have a serious mental health condition.
You currently have a mental illness called psychosis or you are dealing with substance abuse problems that are not under control.
+9 more
Participant Groups
The trial studies the effects of high intensity interval training (HIIT) on women with endometrial cancer before their standard surgery. It aims to see if HIIT has anti-cancer benefits by examining changes in tissue and blood markers.
1Treatment groups
Experimental Treatment
Group I: HIIT exerciseExperimental Treatment1 Intervention
Participants will perform HIIT exercises as instructed by the study team in the weeks prior to standard of care surgery
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC
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Who Is Running the Clinical Trial?
UNC Lineberger Comprehensive Cancer CenterLead Sponsor
National Cancer Institute (NCI)Collaborator