Pre-Surgery Exercise for Frailty

Recruiting in Palo Alto (17 mi)

Overseen byDaniel I McIsaac, MD,MPH,FRCPC

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Ottawa Hospital Research Institute

No Placebo Group

Trial Summary

What is the purpose of this trial?

This study evaluates whether participating in a home-based exercise program leads to lower levels of complication rates and patient-reported disability after surgery. Half of the participants will be randomized into the exercise group, while the other half will be randomized into the control group.

Research Team

Daniel I McIsaac, MD,MPH,FRCPC

Principal Investigator

The Ottawa Hospital Research Institute

Eligibility Criteria

This trial is for people aged 60 or older who are considered frail (with a Clinical Frailty Scale score of at least 4/9) and have elective surgery planned that will require a hospital stay of two days or more. They must be able to start the exercise program between 3 and 12 weeks before their surgery date. Those with certain heart, nerve, or bone conditions, unable to communicate in English or French, having palliative surgeries, or unreachable by phone cannot join.

Inclusion Criteria

My surgery is scheduled between 3 to 12 weeks from now.

I am scheduled for surgery that will require me to stay in the hospital for at least 2 days.

I am 60 years old or older.

See 1 more

Exclusion Criteria

I have had surgery to relieve symptoms.

I cannot communicate in English or French.

I have had heart, brain, or bone surgery.

See 1 more

Treatment Details

Interventions

Exercise Group (Behavioral Intervention)

Trial OverviewThe PREPARE Trial is testing if doing exercises at home before surgery can help reduce complications and disability after surgery in older adults with frailty. Participants are split into two groups randomly: one group follows the exercise program while the other does not.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: Exercise GroupExperimental Treatment1 Intervention

The intervention is a home-based, multimodal exercise prehabilitation program. Exercise is prescribed in one-hour sessions, performed a minimum of three times per week for three weeks, consisting of: 1) strength training, 2) aerobic exercise and 3) flexibility. The intervention group will receive weekly phone calls to gauge adherence, suggest modifications, provide support and track any adverse events.

Group II: Control GroupActive Control1 Intervention

The control group will receive the World Health Organization recommendations for physical activity for people greater or equal to the age of 65 years old pamphlet, as well as a guide to healthy eating for older adults.