~17 spots leftby Dec 2025

Virtual Exercise Program for Kidney Failure

Recruiting in Palo Alto (17 mi)
TJ
Overseen byTania Janaudis-Ferreira, PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre
Disqualifiers: Robust frailty, Structured exercise, Hospitalized, Cognitive impairment, Cardiac condition, others
No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this RCT is to address the feasibility of conducting a 12-week virtual pre-habilitation intervention, which includes exercise and education, in kidney transplant candidates. The intervention also includes a 5-month maintenance phase with independent home exercises (maximum of 8 months of intervention/ended early if the participant undergoes a kidney transplant). The main questions it aims to answer are: * estimate the proportion of screened patients who meet eligibility criteria * estimate the proportion of eligible patients who consent to randomization * estimate the proportion of patients who adhere to the interventions * estimate follow-up completion rates * inform the calculation of sample size requirements for a full-scale RCT * assess the acceptability of the intervention by the participants. Participants in the control group will receive usual outpatient care.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on exercise and education for kidney transplant candidates.

What data supports the effectiveness of the treatment Virtual Home-based Physical Pre-habilitation for kidney failure?

Research shows that telerehabilitation, which involves exercise programs delivered via video calls, can help improve physical performance in older adults and those recovering from hospital stays. This suggests that a virtual exercise program could be beneficial for people with kidney failure as well.12345

Is the virtual exercise program safe for people with kidney failure?

Research shows that home-based exercise programs, including virtual and remote guidance, are generally safe for people with chronic kidney disease, including those awaiting kidney transplantation. These programs have been designed to be safe and effective in improving physical fitness and overall health.678910

How is the Virtual Home-based Physical Pre-habilitation treatment different from other treatments for kidney failure?

The Virtual Home-based Physical Pre-habilitation treatment is unique because it allows patients with kidney failure to engage in exercise programs from home using virtual guidance, which can improve their physical function and readiness for kidney transplantation. This approach is different from traditional in-person rehabilitation as it provides remote supervision and flexibility, making it more accessible for patients who may have difficulty traveling to a center.67111213

Research Team

TJ

Tania Janaudis-Ferreira, PhD

Principal Investigator

Research Institute of McGill University Health Centre (RI-MUHC)

Eligibility Criteria

This trial is for English or French-speaking adults over 18 with end-stage kidney disease who are frail to very frail and on the transplant list at specific Canadian hospitals. They must be able to use videoconferencing, either alone or with help, but those without internet can borrow a tablet.

Inclusion Criteria

I am over 18, have end stage kidney disease, and am on the transplant list.
I speak English or French.
You are technologically able to connect with an online videoconferencing platform by invitation via email, or can access the internet through a borrowed tablet.

Trial Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Pre-habilitation

Participants undergo a 12-week virtual home-based supervised exercise program with educational components

12 weeks
Virtual visits

Maintenance

Participants continue with a 5-month maintenance phase involving independent home exercises

5 months
Virtual check-ins

Follow-up

Participants are monitored for safety and effectiveness after the intervention

3 months post-transplant

Treatment Details

Interventions

  • Virtual Home-based Physical Pre-habilitation (Behavioural Intervention)
Trial OverviewThe study tests if a virtual home-based exercise and education program helps people waiting for kidney transplants. It's a randomized controlled trial comparing this pre-habilitation intervention against usual care over up to 8 months.
Participant Groups
2Treatment groups
Experimental Treatment
Group I: No Intervention: Usual outpatient careExperimental Treatment1 Intervention
The control group will receive usual outpatient care provided to kidney transplant candidates. All participants in the control group will receive educational resources received by intervention group participants at trial completion.
Group II: Experimental: Pre-habilitation plus usual outpatient careExperimental Treatment1 Intervention
An intervention including exercise and education.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Research Institute - McGill University Health Centre (RI-MUHC)Montreal, Canada
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Who Is Running the Clinical Trial?

McGill University Health Centre/Research Institute of the McGill University Health Centre

Lead Sponsor

Trials
476
Patients Recruited
170,000+

The Kidney Foundation of Canada

Collaborator

Trials
16
Patients Recruited
3,200+

Findings from Research

The Effectiveness of Exercise Interventions Supported by Telerehabilitation For Recently Hospitalized Adult Medical Patients: A Systematic Review.Leslie, S., Tan, J., McRae, PJ., et al.[2022]
Effectiveness of guided telerehabilitation on functional performance in community-dwelling older adults: A systematic review.Gamble, CJ., van Haastregt, J., van Dam van Isselt, EF., et al.[2023]
Effectiveness of home-based cardiac telerehabilitation in patients with heart failure: A systematic review and meta-analysis of randomised controlled trials.Gao, Y., Wang, N., Zhang, L., et al.[2023]
Interactive resistance chair to promote strengthening exercise in older adults.Jeong, IC., Finkelstein, J.[2016]
Effectiveness of an interactive virtual telerehabilitation system in patients after total knee arthoplasty: a randomized controlled trial.Piqueras, M., Marco, E., Coll, M., et al.[2022]
Face-to-Face Mentoring, Remotely Supervised Home Exercise Prehabilitation to Improve Physical Function in Patients Awaiting Kidney Transplantation: A Randomized Clinical Trial.Ma, X., Zhang, Z., Peng, M., et al.[2022]
Study on the effect of pre-rehabilitation home-based on patients undergoing kidney transplantation with end-stage renal disease: A study protocol.Ma, X., Zhang, Z., Yao, B., et al.[2023]
The FRAILMar Study Protocol: Frailty in Patients With Advanced Chronic Kidney Disease Awaiting Kidney Transplantation. A Randomized Clinical Trial of Multimodal Prehabilitation.Pérez-Sáez, MJ., Morgado-Pérez, A., Faura, A., et al.[2021]
PREhabilitation of CAndidates for REnal Transplantation (PreCareTx) study: protocol for a hybrid type I, mixed method, randomised controlled trial.Quint, EE., Haanstra, AJ., van der Veen, Y., et al.[2023]
Multicomponent Home-Based Training Program for Chronic Kidney Disease Patients during Movement Restriction.López-Torres, O., Azpeitia-Martínez, C., González-Gross, M., et al.[2023]
Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease.Aoike, DT., Baria, F., Kamimura, MA., et al.[2018]
An intradialytic non-immersive virtual reality exercise programme: a crossover randomized controlled trial.Martínez-Olmos, FJ., Gómez-Conesa, AA., García-Testal, A., et al.[2022]
A pilot study involving 24 kidney transplant candidates showed that a prehabilitation program, consisting of weekly physical therapy and at-home exercises, significantly improved physical activity levels by 64% over two months.
Participants who underwent prehabilitation had a shorter hospital stay after kidney transplant (5 days) compared to matched controls (10 days), suggesting that prehabilitation may enhance recovery outcomes post-transplant.
Prehabilitation prior to kidney transplantation: Results from a pilot study.McAdams-DeMarco, MA., Ying, H., Van Pilsum Rasmussen, S., et al.[2023]

References

The Effectiveness of Exercise Interventions Supported by Telerehabilitation For Recently Hospitalized Adult Medical Patients: A Systematic Review. [2022]
Effectiveness of guided telerehabilitation on functional performance in community-dwelling older adults: A systematic review. [2023]
Effectiveness of home-based cardiac telerehabilitation in patients with heart failure: A systematic review and meta-analysis of randomised controlled trials. [2023]
Interactive resistance chair to promote strengthening exercise in older adults. [2016]
Effectiveness of an interactive virtual telerehabilitation system in patients after total knee arthoplasty: a randomized controlled trial. [2022]
Face-to-Face Mentoring, Remotely Supervised Home Exercise Prehabilitation to Improve Physical Function in Patients Awaiting Kidney Transplantation: A Randomized Clinical Trial. [2022]
Study on the effect of pre-rehabilitation home-based on patients undergoing kidney transplantation with end-stage renal disease: A study protocol. [2023]
The FRAILMar Study Protocol: Frailty in Patients With Advanced Chronic Kidney Disease Awaiting Kidney Transplantation. A Randomized Clinical Trial of Multimodal Prehabilitation. [2021]
PREhabilitation of CAndidates for REnal Transplantation (PreCareTx) study: protocol for a hybrid type I, mixed method, randomised controlled trial. [2023]
Multicomponent Home-Based Training Program for Chronic Kidney Disease Patients during Movement Restriction. [2023]
Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease. [2018]
An intradialytic non-immersive virtual reality exercise programme: a crossover randomized controlled trial. [2022]
Prehabilitation prior to kidney transplantation: Results from a pilot study. [2023]