Prehabilitation Exercise for Kidney Failure
Trial Summary
The trial information does not specify whether you need to stop taking your current medications. Please consult with the trial coordinators or your doctor for guidance.
The available research shows that prehabilitation exercise, which includes physical activity before surgery, can improve a patient's health and recovery. For example, it has been found to enhance fitness and reduce complications after surgery, as seen in patients undergoing heart and cancer surgeries. This suggests that similar benefits might be expected for kidney failure patients. Prehabilitation can also shorten hospital stays and improve quality of life, making it a promising approach compared to usual care.
12345The available research suggests that prehabilitation exercise, including physical therapy and multimodal interventions, is generally safe and feasible for patients with chronic kidney disease (CKD) awaiting kidney transplantation. Studies like the FRAILMar study and a pilot study on prehabilitation prior to kidney transplantation indicate improvements in physical activity, reduced length of hospital stay, and high patient satisfaction. However, contraindications for exercise include recent myocardial infarction, uncontrolled arrhythmia, and other severe conditions. While the benefits are promising, more research is needed to establish standardized protocols and confirm safety across diverse patient populations.
35678Yes, Exercise and Prehabilitation is a promising treatment for kidney failure. It helps improve physical fitness before surgery, which can lead to better recovery and shorter hospital stays after a kidney transplant. Studies show that patients who participate in prehabilitation report high satisfaction and improved physical activity, making it a valuable approach to enhance health outcomes for those awaiting kidney transplants.
23679Eligibility Criteria
This trial is for adults aged 19 or older with chronic kidney failure who are able to do a home-based exercise program and have been cleared for kidney transplantation. They must be patients at Vancouver General Hospital or St. Paul's Hospital, able to read and write in English, and have physician clearance.Inclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Prehabilitation
Participants engage in a home-based exercise program to improve physical functioning before kidney transplantation
Surgery and Immediate Post-Operative Recovery
Participants undergo kidney transplantation and are monitored for immediate post-operative recovery outcomes
Follow-up
Participants are monitored for safety and effectiveness after treatment, including physical fitness assessments and quality of life surveys
Participant Groups
Exercise and Prehabilitation is already approved in European Union, United States, Canada for the following indications:
- Improvement of physical functioning before kidney transplantation
- Reduction of postoperative complications
- Enhancement of preoperative functional capacity
- Improvement of postoperative outcomes in kidney transplant patients
- Mitigation of functional decline in patients awaiting kidney transplantation
- Improvement of quality of life