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Exercise Intervention for Cardiometabolic Health

N/A
Waitlist Available
Led By Jingyi Qian, PhD
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up about 12 and 24 hours after exercise
Awards & highlights
No Placebo-Only Group

Summary

This trial seeks to understand how physical activity affects the body's natural clock. Participants will stay in-hospital, exercise, and provide samples.

Who is the study for?
This trial is for healthy adults aged 20-45 with a BMI of 20-34.9, without any serious health issues like heart disease or cancer. Participants must be willing to follow the study's rules, including staying in the hospital and doing moderate exercise.
What is being tested?
The study aims to see how our body clocks affect physical activity by having participants stay twice in a clinic, do some exercise, eat set meals, and give blood, urine, and saliva samples for testing.
What are the potential side effects?
Since this is an exercise intervention study focusing on healthy individuals without underlying conditions, significant side effects are not expected. However, typical reactions might include muscle soreness or fatigue from the physical activities.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~about 12 and 24 hours after exercise
This trial's timeline: 3 weeks for screening, Varies for treatment, and about 12 and 24 hours after exercise for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
glucose level
mean arterial pressure
Secondary study objectives
autonomic nervous system activity
beta-cell function index
insulin sensitivity index
+1 more
Other study objectives
respiratory exchange ratio
resting energy expenditure

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Exercise B-A InterventionExperimental Treatment1 Intervention
The Exercise B first, then the Exercise A intervention.
Group II: Exercise A-B InterventionExperimental Treatment1 Intervention
The Exercise A first, then the Exercise B intervention.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exercise intervention
2010
Completed Phase 4
~2160

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor
1,666 Previous Clinical Trials
11,840,209 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,935 Previous Clinical Trials
47,792,295 Total Patients Enrolled
Jingyi Qian, PhDPrincipal InvestigatorBrigham and Women's Hospital

Media Library

Exercise intervention Clinical Trial Eligibility Overview. Trial Name: NCT05838508 — N/A
Lifestyle Research Study Groups: Exercise A-B Intervention, Exercise B-A Intervention
Lifestyle Clinical Trial 2023: Exercise intervention Highlights & Side Effects. Trial Name: NCT05838508 — N/A
Exercise intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT05838508 — N/A
~17 spots leftby Aug 2026
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