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Chart review, RNA sequencing, microarray for Primary Effusion Lymphoma

N/A
Waitlist Available
Led By Erin Reid
Research Sponsored by AIDS Malignancy Consortium
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 2 years post diagnosis
Awards & highlights

Summary

This research trial studies clinical factors and gene expression analysis for prognosis in tissue samples from patients with acquired immune deficiency syndrome (AIDS)-related primary effusion lymphoma. Gathering health information over time and studying samples of tissue from patients in the laboratory may help doctors learn about the prognosis of patients with AIDS-related primary effusion lymphoma.

Eligible Conditions
  • Primary Effusion Lymphoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 2 years post diagnosis
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 2 years post diagnosis for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Differential gene expression profile by RNA-Seq or GeneChip assays
Response rates
Survival

Trial Design

1Treatment groups
Experimental Treatment
Group I: Chart review, RNA sequencing, microarrayExperimental Treatment2 Interventions
Laboratory Biomarker Analysis. Medical chart review is performed and patient information is collected regarding human immunodeficiency virus HIV/AIDS medical history, staging of AIDS related malignancy, and type of treatment. Previously collected tissue samples are analyzed via RNA sequencing and microarray.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Laboratory Biomarker Analysis
2010
Completed Phase 2
~890

Find a Location

Who is running the clinical trial?

AIDS Malignancy ConsortiumLead Sponsor
63 Previous Clinical Trials
9,605 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,789 Previous Clinical Trials
40,986,274 Total Patients Enrolled
University of California, San DiegoOTHER
1,148 Previous Clinical Trials
1,557,368 Total Patients Enrolled
~2 spots leftby Sep 2025
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