~2 spots leftby May 2025

Wheelchair Exercise Training for Multiple Sclerosis

Recruiting in Palo Alto (17 mi)
Overseen byStephanie L Silveira, PhD
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of North Texas, Denton, TX
No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this randomized controlled clinical trial is to examine the feasibility and initial efficacy of undertaking and delivering a novel, stakeholder-informed exercise training program for wheelchair users with multiple sclerosis. The main questions it aims to answer are: * Is the study feasible as measured by participant recruitment (24 participants total), retention (80%), and safety (adverse events)? * Is the study acceptable as measured by participant satisfaction and perceptions using an evaluation survey and semi-structured interviews? * Is there significant change in following the 16-week study in metabolic health outcomes, MS symptoms, and exercise behavior change? Participants will be randomized to complete the 16-week SPIN exercise training program or WellMS attention/contact wellness program. Researchers will compare the SPIN and WellMS groups to determine if there is a significant difference in metabolic health outcomes, MS symptoms, and exercise behavior change.

Eligibility Criteria

This trial is for adults over 18 with Multiple Sclerosis who are mostly wheelchair users and not currently active, meaning they don't do regular physical activity more than twice a week. They must have been relapse-free for the last month and will need a doctor's okay if there are health concerns that usually suggest exercise isn't safe.

Inclusion Criteria

I have been diagnosed with multiple sclerosis (MS).
I use a wheelchair more than half of the time.
I have not had a relapse in the last 30 days.
See 2 more

Exclusion Criteria

I passed a health screen for exercise or have doctor's clearance.

Treatment Details

Interventions

  • Seated Physical activity INtervention for persons with MS, 'SPIN' program (Behavioural Intervention)
  • Wellness for MS (WellMS)- Control Condition (Behavioural Intervention)
Trial OverviewThe study tests a new exercise program called SPIN against a wellness program named WellMS in people with MS using wheelchairs. It looks at how well these programs work by checking participant numbers, satisfaction, safety, changes in metabolic health, MS symptoms, and whether participants stick to exercising after the 16-week course.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Exercise Training InterventionExperimental Treatment1 Intervention
Group II: Wellness ControlActive Control1 Intervention

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
The University of Texas Health Science Center at HoustonHouston, TX
Loading ...

Who Is Running the Clinical Trial?

University of North Texas, Denton, TXLead Sponsor
The University of Texas Health Science Center, HoustonLead Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Collaborator
Craig HospitalCollaborator
University of Illinois at ChicagoCollaborator

References