Radiosurgery for Brain Tumor
Trial Summary
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Research shows that stereotactic radiosurgery (SRS), including Gamma Knife radiosurgery, is effective for treating brain metastases and can improve survival when used with or instead of whole-brain radiation therapy. It is also used for other brain conditions like meningiomas and pituitary adenomas, suggesting its effectiveness in targeting specific brain areas with high precision.
12345Radiosurgery, including Stereotactic Radiosurgery (SRS) and Gamma Knife Radiosurgery, is generally considered safe for treating various brain conditions, though there are rare reports of it being associated with new malignancies. Safety checklists are used to minimize errors and complications, and it has been proven safe for many patients, although the risks for larger tumors are less understood.
678910Radiosurgery (SRS) is unique because it uses focused beams of radiation to target brain tumors precisely, allowing treatment of deep-seated areas without invasive surgery. It is often used for brain metastases and can be an alternative to whole-brain radiation therapy, offering a non-invasive option with potentially fewer side effects.
211121314Eligibility Criteria
This trial is for patients with certain types of cancer that have spread to the brain, specifically those with 1-4 brain metastases where at least one lesion is sizable but operable. Participants must be physically able to undergo surgery and radiosurgery, have a good performance status (Karnofsky score β₯ 70), and not have specific cancers like small cell lung cancer or lymphoma.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Radiosurgery
Participants undergo radiosurgery to focus x-rays directly on the tumor
Surgical Resection
Within 2 weeks of radiosurgery, participants undergo surgical resection of brain metastases
Follow-up
Participants are monitored for safety, effectiveness, and long-term outcomes after treatment
Participant Groups
Radiosurgery is already approved in United States, European Union, Canada, Japan for the following indications:
- Brain metastases
- Arteriovenous malformations (AVMs)
- Benign brain tumors
- Malignant brain tumors
- Brain metastases
- Arteriovenous malformations (AVMs)
- Benign brain tumors
- Malignant brain tumors
- Brain metastases
- Arteriovenous malformations (AVMs)
- Benign brain tumors
- Malignant brain tumors
- Brain metastases
- Arteriovenous malformations (AVMs)
- Benign brain tumors
- Malignant brain tumors