Trial Summary
What is the purpose of this trial?The goal of this research study is to learn if a home-based physical activity program is feasible and can help endometrial cancer survivors lose weight.
Eligibility Criteria
This trial is for Stage I-II endometrial cancer survivors with a BMI of 30-<45, who are 6-36 months post-treatment, over 18 years old, and have access to a phone and internet. Participants must be able to visit the campus twice, speak English, consent to the study, and not be doing much exercise or in another weight loss program.Inclusion Criteria
Your body mass index (BMI) is between 30 and less than 45 kg/m2.
Diagnosed with Stage I-II endometrial cancer
Six to 36 months post treatment
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Exclusion Criteria
You have medical conditions that make it unsafe for you to do exercise at home or follow a low-fat, high fruit and vegetable diet.
Functional limitations requiring a walker/scooter/wheelchair for daily activities
You participate in strength training exercises for at least 30 minutes, on 2 or more days every week.
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Participant Groups
The study tests if a home-based physical activity program can help these survivors lose weight. It includes using an accelerometer (like Fitbit), answering questionnaires, resistance training through video chats, fitness testing, and receiving telephone coaching.
3Treatment groups
Experimental Treatment
Active Control
Group I: NEXT-Steps- Aerobic Exercise and Resistance Training (NS-ART)Experimental Treatment6 Interventions
Participant wears an accelerometer for 7 days before baseline visit. Six questionnaires completed regarding quality of life and diet. Fitness test given covering various physical activities at baseline and at 6 month visit.
Participants placed into an exercise plan focused on physical activity and resistance training. Physical activity guidelines workbook distributed along with activity monitor. Participants receive phone calls and text messages for support in reaching exercise and diet goals.
Participants receive resistance bands to perform resistance exercises. Exercise handouts and an iPad mini with training videos used to video chat with a research team member.
Questionnaires completed at 3 and 6 months regarding quality of life, diet, physical activity, etc.
Group II: NEXT-Steps- Aerobic Exercise (NS-A)Experimental Treatment5 Interventions
Participant wears an accelerometer for 7 days before baseline visit. Six questionnaires completed regarding quality of life and diet. Fitness test given covering various physical activities at baseline and at 6 month visit.
Participants placed into an exercise plan focused on physical activity only. Physical activity guidelines workbook distributed along with activity monitor. Participants receive phone calls and text messages for support in reaching exercise and diet goals.
Questionnaires completed at 3 and 6 months regarding quality of life, diet, physical activity, etc.
Group III: Standard Care Control Group (CG)Active Control4 Interventions
Participant wears an accelerometer for 7 days before baseline visit. Six questionnaires completed regarding quality of life and diet. Fitness test given covering various physical activities at baseline and at 6 month visit.
Participants receive standard of care consisting of phone calls asking about their health and self-help materials.
Questionnaires completed at 3 and 6 months regarding quality of life, diet, physical activity, etc.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
University of Texas MD Anderson Cancer CenterHouston, TX
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Who Is Running the Clinical Trial?
M.D. Anderson Cancer CenterLead Sponsor
National Cancer Institute (NCI)Collaborator