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Speech Tasks for Speech Perception

N/A

Waitlist Available

Led By Edward F Chang, MD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Participants who lack capacity or decline to provide informed consent

Participants with cognitive deficits that preclude reliable completion of study tasks

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during procedure

Awards & highlights

No Placebo-Only Group

Summary

This trial is investigating how the brain extracts linguistic elements from speech sounds in order to better understand and treat human language disorders.

Who is the study for?

This trial is for individuals at UCSF with epilepsy or brain tumors who are undergoing surgical electrode implantation. They must have electrodes in at least two key brain areas and be able to perform study tasks. Those unable to consent, with significant cerebral lesions, or cognitive deficits that prevent task completion cannot participate.

What is being tested?

The study investigates how the superior temporal gyrus of the brain processes speech sounds. Participants will perform speech tasks while their brain activity is monitored to understand how we perceive words and continuous speech, aiming to improve language disorder treatments.

What are the potential side effects?

Since this trial involves non-invasive speech tasks without drugs or medical procedures beyond those already required for participants' clinical care, there are no direct side effects from the interventions being studied.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am unable or unwilling to give consent for this trial.

Select...

I am able to understand and complete study tasks despite any cognitive issues.

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I have significant brain lesions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during procedure

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during procedure

This trial's timeline: 3 weeks for screening, Varies for treatment, and during procedure for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Number of Participants with Electrocorticography (ECoG) Signals for Neural Activity Identified During Intraoperative Procedure or Inpatient Hospitalization

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Electrocorticography (ECoG) recording during Speech TasksExperimental Treatment1 Intervention

Participants listened to 25-minute Speech Tasks while ECoG signals for neural activity was recorded during their intraoperative procedure or inpatient hospitalization at the University of California, San Francisco (UCSF).

0 / 3Eligibility criteria met