← Back to Search

Behavioral Intervention

Peer-led Intervention for Opioid Use Disorder (THRIVE Trial)

Pittsburgh, PA

N/A

Recruiting

Led By Jacqueline D Wilson, MD

Research Sponsored by University of Pennsylvania

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Participants must be at least 18 years of age on day of admission

Be older than 18 years old

Must not have

Participants diagnosed with dementia and/or cognitive impairments

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 6 months

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to test a new program called the THRIVE intervention, which provides peer-led harm reduction services in hospitals. The study wants to find out if participants in the THRIVE intervention have a lower

See full description

Who is the study for?

This trial is for individuals with Opioid Use Disorder who may also be at risk of self-harm. Participants should be currently hospitalized and willing to engage with peer support specialists, as well as comfortable receiving and responding to text messages for assessments.Check my eligibility

What is being tested?

The THRIVE intervention, which includes a one-time in-person session with a peer specialist, weekly follow-up texts for 12 weeks, and regular text message assessments over six months, is being tested against enhanced usual care that provides harm reduction resources without the personalized support.See study design

What are the potential side effects?

Since this study involves educational interventions rather than medications or medical procedures, traditional side effects are not expected. However, participants might experience emotional discomfort discussing sensitive topics related to opioid use.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am at least 18 years old.

show original

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have been diagnosed with dementia or cognitive impairments.

show original

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Effectiveness of the THRIVE intervention compared to enhanced usual care (EUC) at lowering the incidence of non-fatal overdoses OR skin and soft tissue infections

Secondary study objectives

Effectiveness of the THRIVE intervention compared to EUC at lowering the incidence of non-fatal overdoses

Effectiveness of the THRIVE intervention compared to EUC at lowering the incidence of skin and soft tissue infections

Other study objectives

Effectiveness of the THRIVE intervention on change in harm reduction adoption compared to EUC (a)

Effectiveness of the THRIVE intervention on change in harm reduction adoption compared to EUC (b)

Effectiveness of the THRIVE intervention on change in harm reduction adoption compared to EUC (c)

+5 more