Resistance Training for Cerebral Palsy (RIPT Trial)
Palo Alto (17 mi)Overseen byElizabeth Condliffe
Age: < 18
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: N/A
Recruiting
Sponsor: University of Calgary
No Placebo Group
Trial Summary
What is the purpose of this trial?Changes related to Cerebral Palsy (CP) include differences in muscle architecture and cortical activity. These result in weakness, decreased functional ability and limited participation in physical activity. Strength training programs, particularly those including power training components, show great potential in improving the gross motor function of youth with CP. However, this intervention is not currently offered in the Calgary area. Delivered via an innovative partnership with community stakeholders, this project will investigate the preliminary effectiveness of the program to enable youth with CP to achieve child and family centered goals. It will also investigate the feasibility of offering this type of program via a community-hospital partnership.
Research Question \& Objectives:
1. Can youth with cerebral palsy achieve their goals and improve their motor function through RIPT (Resistance Intensive Personal Training), a power training program offered jointly by specialized physiotherapists and fitness professionals in community settings?
2. What are the barriers and facilitators to delivery of RIPT in a community setting for youth, caregivers, clinicians, and program staff?
What safety data exists for resistance training in cerebral palsy?The available research indicates that resistance training, including explosive and progressive heavy-resistance training, can improve muscle strength and gait function in individuals with cerebral palsy. However, the systematic review highlights limited evidence on functional improvements and identifies a need for more research on safety and specific program design. No adverse safety data is explicitly mentioned, suggesting that resistance training is generally considered safe, but specific risks and considerations should be taken into account when designing training programs for this population.125812
What data supports the idea that Resistance Training for Cerebral Palsy is an effective treatment?The available research shows that resistance training can be an effective treatment for cerebral palsy. One study compared resistance training to treadmill training and found that both improved motor function in adolescents with cerebral palsy. Another study highlighted that intensive physical exercise, which includes resistance training, improved outcomes in children with cerebral palsy, especially when the number of daily training hours was increased. Additionally, a case report described improvements in functional movement and strength after a 3-month resistance training program for an adolescent with cerebral palsy. These findings suggest that resistance training can help improve motor skills and strength in individuals with cerebral palsy.347911
Is Resistance Intensive Personal Training a promising treatment for people with cerebral palsy?Yes, Resistance Intensive Personal Training is promising for people with cerebral palsy. It can improve physical work capacity, increase muscle strength, and enhance movement abilities like walking. This type of training helps people with cerebral palsy perform daily tasks better and may also improve their sports performance.2681012
Do I have to stop taking my current medications for this trial?The trial protocol does not specify whether you need to stop taking your current medications.
Eligibility Criteria
This trial is for young people with Cerebral Palsy, aged 8 to 17 years old, who can understand English and are capable of exerting maximum effort in physical activities. It's not suitable for those who don't meet these age or communication requirements.Inclusion Criteria
I am 17 years old or younger.
I am at least 8 years old.
Treatment Details
The study tests a Resistance Intensive Personal Training program designed to improve muscle strength and motor function in youth with CP. The effectiveness and feasibility of delivering this training through a community-hospital partnership are being evaluated.
1Treatment groups
Experimental Treatment
Group I: Resistance Intensive Personal Training (RIPT)Experimental Treatment1 Intervention
All participants will participate in this arm involving 12 weeks of training 2-3 days/week in a group setting with each session involving 1:1 support for each participant's power training.
Find a clinic near you
Research locations nearbySelect from list below to view details:
Alberta Children's HospitalCalgary, Canada
Loading ...
Who is running the clinical trial?
University of CalgaryLead Sponsor
References
Effects of quadriceps femoris muscle strengthening on crouch gait in children with spastic diplegia. [2019]Despite evidence of weakness in children with cerebral palsy, the use of strength training in this population remains controversial.
Training of ambulatory individuals with cerebral palsy. [2019]The effect of training on the physical work capacity (PWC) and the physiological response to simulated tasks of seven ambulatory individuals with cerebral palsy (CP) were studied. Energy demand for each work task was determined by percentage of PWC (%PWC). Results indicate that an eight week training program increased the PWC as evaluated by an exercise test on the Schwinn Air-Dyne Ergometer. The performance of the individuals for the simulated tasks measured in %PWC increased significantly, suggesting that individuals with CP could benefit from a training program and would be able to work eight hours before experiencing fatigue.
Change in basic motor abilities, quality of movement and everyday activities following intensive, goal-directed, activity-focused physiotherapy in a group setting for children with cerebral palsy. [2022]The effects of intensive training for children with cerebral palsy (CP) remain uncertain. The aim of the study was to investigate the impact on motor function, quality of movements and everyday activities of three hours of goal-directed activity-focused physiotherapy in a group setting, five days a week for a period of three weeks.
Neurorehabilitation with versus without resistance training after botulinum toxin treatment in children with cerebral palsy: a randomized pilot study. [2012]To compare the effects of physical rehabilitation with (PRT) and without (CON) progressive resistance training following treatment of spastic plantarflexors with botulinum toxin type A (BoNT) in children with cerebral palsy (CP).
Differential adaptations of muscle architecture to high-velocity versus traditional strength training in cerebral palsy. [2022]Everyday activities for youth with cerebral palsy (CP) require muscle power, but the velocity component of muscle contraction is neglected with traditional strength training (ST).
Progressive resistance training and mobility-related function in young people with cerebral palsy: a randomized controlled trial. [2015]The aim of this study was to investigate whether individualized resistance training improves the physical mobility of young people with cerebral palsy (CP).
Functional movement, strength, and intervention for an adolescent with cerebral palsy. [2015]This case report describes the examination, intervention, and outcome of a 3-month episode of physical therapy (PT) using combined functional training and progressive resistance exercise for an adolescent with cerebral palsy.
Explosive Resistance Training Increases Rate of Force Development in Ankle Dorsiflexors and Gait Function in Adults With Cerebral Palsy. [2018]Kirk, H, Geertsen, SS, Lorentzen, J, Krarup, KB, Bandholm, T, and Nielsen, JB. Explosive resistance training increases rate of force development in ankle dorsiflexors and gait function in adults with cerebral palsy. J Strength Cond Res 30(10): 2749-2760, 2016-Alterations in passive elastic properties of muscles and reduced ability to quickly generate muscle force contribute to impaired gait function in adults with cerebral palsy (CP). In this study, we investigated whether 12 weeks of explosive and progressive heavy-resistance training (PRT) increases rate of force development of ankle dorsiflexors (RFDdf), improves gait function, and affects passive ankle joint stiffness in adults with CP. Thirty-five adults (age: 36.5; range: 18-59 years) with CP were nonrandomly assigned to a PRT or nontraining control (CON) group in this explorative trial. The PRT group trained ankle dorsiflexion, plantarflexion, leg press, hamstring curls, abdominal curls, and back extension 3 days per week for 12 weeks, with 3 sets per exercise and progressing during the training period from 12 to 6 repetition maximums. RFDdf, 3-dimensional gait analysis, functional performance, and ankle joint passive and reflex-mediated muscle stiffness were evaluated before and after. RFDdf increased significantly after PRT compared to CON. PRT also caused a significant increase in toe lift late in swing and a significantly more dorsiflexed ankle joint at ground contact and during stance. The increased toe-lift amplitude was correlated to the increased RFDdf (r = 0.73). No other between-group differences were observed. These findings suggest that explosive PRT may increase RFDdf and facilitate larger range of movement in the ankle joint during gait. Explosive PRT should be tested in clinical practice as part of a long-term training program for adults with CP.
Effects of a group circuit progressive resistance training program compared with a treadmill training program for adolescents with cerebral palsy. [2018]To determine whether goal-directed group circuit progressive resistance exercise training (GT) can improve motor function in adolescents with cerebral palsy (CP) and to compare outcomes with a treadmill training (TT) intervention.
The Effect of Functional Home-Based Strength Training Programs on the Mechano-Morphological Properties of the Plantar Flexor Muscle-Tendon Unit in Children With Spastic Cerebral Palsy. [2019]The purpose of this study was to investigate the effects of functional progressive resistance training (PRT) and high-intensity circuit training (HICT) on the mechano-morphological properties of the plantar flexor muscle-tendon unit in children with spastic cerebral palsy.
Effects of Therapeutic Exercise Intensity on Cerebral Palsy Outcomes: A Systematic Review With Meta-Regression of Randomized Clinical Trials. [2023]Background and Objective: Intensive physical therapy or exercise has been associated with favorable cerebral palsy (CP) outcomes, but few studies have investigated the effects of exercise intensity on the improvement in CP outcomes. In this study, we assessed the effects of intensive exercise-based therapy on improvement in gross motor function in children with CP. Methods: We searched three databases for randomized clinical trials evaluating the effects of therapeutic exercise training by using Gross Motor Function Measurement (GMFM) 66 and 88 among children with CP. Studies that used interventions in addition to therapeutic exercise were excluded from the present meta-analysis. Exercise intensity was defined using the number of training hours per day and duration of intervention (in weeks). The effects of the number of daily training hours and program duration on GMFM improvement were evaluated using meta-regression. Results: The comprehensive search returned 270 references, and 13 of 270 references met our eligibility criteria. The 13 trials recruited 412 children with CP. These trials measured motor improvements by using GMFM-66 (n = 8) and GMFM-88 (n = 5). The GMFM scores in the children who received the therapeutic intervention did not show significantly greater improvement than those of the children who received standard care. Meta-regression analysis revealed that the improvement in GMFM scores was positively associated with the number of daily training hours (point estimate = 0.549; p = 0.031) and program duration (point estimate = 0.067; p = 0.075). Discussion and Conclusions: Intensive physical exercise improved CP outcomes in the intervention and standard therapy groups. The duration of therapeutic intervention improved CP outcomes among the children who received the therapeutic intervention, while an increase in the number of daily training hours improved in CP outcomes in the children who received standard therapy.
Strength Training to Improve Performance in Athletes With Cerebral Palsy: A Systematic Review of Current Evidence. [2021]Fleeton, JRM, Sanders, RH, and Fornusek, C. Strength training to improve performance in athletes with cerebral palsy: A systematic review of current evidence. J Strength Cond Res 34(6): 1774-1789, 2020-Persons with cerebral palsy (CP) can partake in many different forms of organized sport including elite competition at state and international levels. There is limited evidence on how CP athletes should train to enhance performance. The purposes of this article were to conduct a systematic review of the current evidence on ambulatory individuals with CP for (a) strength and functional improvement through strength training; (b) potential sports performance improvement through strength training; (c) the identification of risk and special considerations associated with strength and conditioning for this population, and; (d) the identification of future research foci to educate strength and conditioning coaches on specific program design for elite CP athletes. Seven electronic databases were searched for studies investigating resistance training interventions. The databases were also searched for training interventions or investigations into sports performance in athletes with CP competing at regional level or above. Thirty articles were included in the systematic review of strength training, and 23 articles included in the narrative review of training for sports performance. High-quality evidence indicates that resistance training can improve muscular strength in individuals with CP, with some preliminary evidence of structural and neurological adaptations. However, there is limited evidence for functional improvements. Limited research has examined the performance capacity of athletes with CP, and no training interventions have been conducted. Coaches should employ existing guidelines when designing programs while considering specific athlete limitations. Initially, the focus should be increasing athlete muscular strength before considering specific sport demands.