~1 spots leftby Jun 2025

Resistance Training for Cerebral Palsy

(RIPT Trial)

Recruiting in Palo Alto (17 mi)
EC
Overseen byElizabeth Condliffe
Age: < 18
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: University of Calgary
Disqualifiers: Acute pathology, High neuromotor impairment, others
No Placebo Group

Trial Summary

What is the purpose of this trial?

Changes related to Cerebral Palsy (CP) include differences in muscle architecture and cortical activity. These result in weakness, decreased functional ability and limited participation in physical activity. Strength training programs, particularly those including power training components, show great potential in improving the gross motor function of youth with CP. However, this intervention is not currently offered in the Calgary area. Delivered via an innovative partnership with community stakeholders, this project will investigate the preliminary effectiveness of the program to enable youth with CP to achieve child and family centered goals. It will also investigate the feasibility of offering this type of program via a community-hospital partnership. Research Question \& Objectives: 1. Can youth with cerebral palsy achieve their goals and improve their motor function through RIPT (Resistance Intensive Personal Training), a power training program offered jointly by specialized physiotherapists and fitness professionals in community settings? 2. What are the barriers and facilitators to delivery of RIPT in a community setting for youth, caregivers, clinicians, and program staff?

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What data supports the effectiveness of the treatment Resistance Intensive Personal Training, Resistance Training, Power Training, Intensive Personal Training for cerebral palsy?

Research shows that intensive physical exercise, including resistance training, can improve motor function in children with cerebral palsy. Studies found that more daily training hours and longer program durations are linked to better outcomes in motor skills.12345

Is resistance training safe for people with cerebral palsy?

Research suggests that resistance training, including explosive and progressive heavy-resistance training, is generally safe for individuals with cerebral palsy. Studies have shown improvements in muscle strength and function without significant adverse effects, indicating it can be a safe part of a training program.678910

How is the Resistance Intensive Personal Training treatment different from other treatments for cerebral palsy?

Resistance Intensive Personal Training is unique because it focuses on explosive and progressive resistance exercises to improve muscle strength and gait function in individuals with cerebral palsy, which is not typically emphasized in other treatments. This approach aims to enhance the ability to quickly generate muscle force, leading to better movement and reduced fatigue.78101112

Research Team

EC

Elizabeth Condliffe

Principal Investigator

University of Calgary

Eligibility Criteria

This trial is for young people with Cerebral Palsy, aged 8 to 17 years old, who can understand English and are capable of exerting maximum effort in physical activities. It's not suitable for those who don't meet these age or communication requirements.

Inclusion Criteria

I am 17 years old or younger.
able to follow directions in English
I can perform activities requiring my full effort.
See 1 more

Trial Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo Resistance Intensive Personal Training (RIPT) for 12 weeks, 2-3 days per week, with 1:1 support in a group setting

12 weeks
2-3 visits per week (in-person)

Follow-up

Participants and families complete assessments and participate in focus groups to evaluate the program's effectiveness and feasibility

2 weeks
1-2 visits (in-person)

Evaluation

Evaluation of outcomes using Goal Attainment Scale, EQ-5D-Y, and other measures to assess the impact of the training program

14 weeks

Treatment Details

Interventions

  • Resistance Intensive Personal Training (Behavioural Intervention)
Trial OverviewThe study tests a Resistance Intensive Personal Training program designed to improve muscle strength and motor function in youth with CP. The effectiveness and feasibility of delivering this training through a community-hospital partnership are being evaluated.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Resistance Intensive Personal Training (RIPT)Experimental Treatment1 Intervention
All participants will participate in this arm involving 12 weeks of training 2-3 days/week in a group setting with each session involving 1:1 support for each participant's power training.

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Alberta Children's HospitalCalgary, Canada
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Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials
827
Patients Recruited
902,000+

Findings from Research

Effects of a group circuit progressive resistance training program compared with a treadmill training program for adolescents with cerebral palsy.Aviram, R., Harries, N., Namourah, I., et al.[2018]
Change in basic motor abilities, quality of movement and everyday activities following intensive, goal-directed, activity-focused physiotherapy in a group setting for children with cerebral palsy.Sorsdahl, AB., Moe-Nilssen, R., Kaale, HK., et al.[2022]
Effects of Therapeutic Exercise Intensity on Cerebral Palsy Outcomes: A Systematic Review With Meta-Regression of Randomized Clinical Trials.Hsu, CW., Kang, YN., Tseng, SH.[2023]
A 3-month physical therapy program combining functional training and progressive resistance exercise led to significant improvements in lower extremity strength for an adolescent with cerebral palsy.
While improvements in functional strength, agility, and anaerobic power were clinically insignificant, the patient reported enhanced participation in activities and achieved new functional movements, highlighting the importance of personalized goals in therapy.
Functional movement, strength, and intervention for an adolescent with cerebral palsy.Hedgecock, JB., Rapport, MJ., Sutphin, AR.[2015]
Neurorehabilitation with versus without resistance training after botulinum toxin treatment in children with cerebral palsy: a randomized pilot study.Bandholm, T., Jensen, BR., Nielsen, LM., et al.[2012]
Differential adaptations of muscle architecture to high-velocity versus traditional strength training in cerebral palsy.Moreau, NG., Holthaus, K., Marlow, N.[2022]
Explosive Resistance Training Increases Rate of Force Development in Ankle Dorsiflexors and Gait Function in Adults With Cerebral Palsy.Kirk, H., Geertsen, SS., Lorentzen, J., et al.[2018]
Training of ambulatory individuals with cerebral palsy.Fernandez, JE., Pitetti, KH.[2019]
Effects of quadriceps femoris muscle strengthening on crouch gait in children with spastic diplegia.Damiano, DL., Kelly, LE., Vaughn, CL.[2019]
Strength Training to Improve Performance in Athletes With Cerebral Palsy: A Systematic Review of Current Evidence.Fleeton, JRM., Sanders, RH., Fornusek, C.[2021]
Progressive resistance training and mobility-related function in young people with cerebral palsy: a randomized controlled trial.Taylor, NF., Dodd, KJ., Baker, RJ., et al.[2015]
The Effect of Functional Home-Based Strength Training Programs on the Mechano-Morphological Properties of the Plantar Flexor Muscle-Tendon Unit in Children With Spastic Cerebral Palsy.Kruse, A., Schranz, C., Svehlik, M., et al.[2019]

References

Effects of a group circuit progressive resistance training program compared with a treadmill training program for adolescents with cerebral palsy. [2018]
Change in basic motor abilities, quality of movement and everyday activities following intensive, goal-directed, activity-focused physiotherapy in a group setting for children with cerebral palsy. [2022]
Effects of Therapeutic Exercise Intensity on Cerebral Palsy Outcomes: A Systematic Review With Meta-Regression of Randomized Clinical Trials. [2023]
Functional movement, strength, and intervention for an adolescent with cerebral palsy. [2015]
Neurorehabilitation with versus without resistance training after botulinum toxin treatment in children with cerebral palsy: a randomized pilot study. [2012]
Differential adaptations of muscle architecture to high-velocity versus traditional strength training in cerebral palsy. [2022]
Explosive Resistance Training Increases Rate of Force Development in Ankle Dorsiflexors and Gait Function in Adults With Cerebral Palsy. [2018]
Training of ambulatory individuals with cerebral palsy. [2019]
Effects of quadriceps femoris muscle strengthening on crouch gait in children with spastic diplegia. [2019]
10.United Statespubmed.ncbi.nlm.nih.gov
Strength Training to Improve Performance in Athletes With Cerebral Palsy: A Systematic Review of Current Evidence. [2021]
Progressive resistance training and mobility-related function in young people with cerebral palsy: a randomized controlled trial. [2015]
12.United Statespubmed.ncbi.nlm.nih.gov
The Effect of Functional Home-Based Strength Training Programs on the Mechano-Morphological Properties of the Plantar Flexor Muscle-Tendon Unit in Children With Spastic Cerebral Palsy. [2019]