Advanced DBS Programming for Parkinson's Disease

N/A

Waitlist Available

Research Sponsored by University of Toronto

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Individuals with idiopathic Parkinson's disease who previously underwent DBS surgery

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up first programming (baseline) - crossover programming (1 month follow-up)- third month follow-up

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing the effectiveness of a newer neurostimulator vs. an older one for people with Parkinson's Disease, with 3 clinic visits over 1 year. Primary outcome is patient-reported global impression of change (PGIC).

Who is the study for?

This trial is for Parkinson's disease patients who've had Deep Brain Stimulation (DBS) surgery and upgraded their neurostimulator from Activa PC to Medtronic PerceptTM PC. Participants must be able to give informed consent.

What is being tested?

The study tests the effectiveness of programming DBS with the full capabilities of the Percept PC neurostimulator compared to older settings. It's a double-blinded, randomized, cross-over trial involving three clinic visits over one year.

What are the potential side effects?

While specific side effects are not listed, reprogramming a neurostimulator may cause temporary discomfort or changes in motor symptoms until optimal settings are found.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have Parkinson's and had DBS surgery.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ first programming (baseline) - crossover programming (1 month follow-up)- third month follow-up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~first programming (baseline) - crossover programming (1 month follow-up)- third month follow-up

This trial's timeline: 3 weeks for screening, Varies for treatment, and first programming (baseline) - crossover programming (1 month follow-up)- third month follow-up for reporting.