Ultrasound Perfusion Measurement for Peripheral Artery Disease

Palo Alto (17 mi)

Overseen byAzra Alizad, MD

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Waitlist Available

Sponsor: Mayo Clinic

No Placebo Group

Approved in 3 jurisdictions

Trial Summary

What is the purpose of this trial?The purpose of this study is to evaluate the potential of ultrasound perfusion imaging technique for assessing the progression of peripheral arterial disease (PAD) and monitoring its response to therapy by measuring changes in microvessel alterations and perfusion variations.

Eligibility Criteria

This trial is for men and women over 18 who have symptoms of claudication, which often indicates peripheral arterial disease (PAD), and are scheduled for vascular testing. It's not suitable for patients with gangrene, lower leg amputations, ulcers, or conditions that prevent ultrasound use. Vulnerable populations are also excluded.

Exclusion Criteria

I have had an amputation below the knee.

I have an ulcer or a condition that prevents ultrasound use.

I have gangrene.

Treatment Details

The study is exploring the effectiveness of an ultrasound technique to track how PAD progresses and responds to treatment by looking at changes in tiny blood vessels and blood flow.

1Treatment groups

Experimental Treatment

Group I: Early detection of PAD, assessment of the disease progression and treatment responseExperimental Treatment1 Intervention

The objective of this arm of the study is to evaluate the potentials of Ultrasound Perfusion imaging technique for early detection of peripheral arterial disease in patients and assess the disease progression and monitor the treatment response. The investigators anticipate that our new cost-effective and non-invasive ultrasound perfusion technique offers a quantitative perfusion estimation of calf muscle that would separate PAD from non-PAD and help early detection of PAD and would help monitoring the disease progression and treatment response.