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Neurofeedback

Neurofeedback for Borderline Personality Disorder

N/A

Recruiting

Led By Kymberl Young, PhD

Research Sponsored by Kymberly Young

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Must not have

Have a clinically significant or unstable cardiovascular, pulmonary, endocrine, neurological, gastrointestinal illness or unstable medical disorder

Serious suicidal ideation

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline vs 12 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether increasing the amygdala's response to positive memories through rtfMRI-nf training can help borderline personality disorder.

Who is the study for?

This trial is for right-handed English-speaking adults aged 18-55 with Borderline Personality Disorder, as diagnosed by specific criteria. Participants must be able to consent and should either not be on medication or stable on SSRI antidepressants for at least three weeks.

What is being tested?

The study tests if a type of brain training called rtfMRI-nf, which aims to increase the amygdala's response to positive memories, can help people with Borderline Personality Disorder.

What are the potential side effects?

Since this trial involves neurofeedback rather than medication, traditional side effects are not expected. However, participants may experience discomfort from being in an MRI machine.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I do not have any serious or unstable health conditions.

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I have had serious thoughts about taking my own life.

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I have been diagnosed with a severe mental health condition.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline vs 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline vs 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline vs 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change from Baseline in Borderline Scale from the Personality Assessment Inventory at 12 weeks

Secondary study objectives

Change from Baseline in Beck Depression Inventory at 12 weeks

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Amygdala NeurofeedbackExperimental Treatment1 Intervention

Participants will undergo real-time fMRI neurofeedback training to increase their amygdala response while recalling positive autobiographical memories. 2 sessions will occur within a one week period.

0 / 3Eligibility criteria met