Golden Halo, Static Magnetic and Electric Field Device, in Recurrent Glioblastoma

Recruiting in Palo Alto (17 mi)

Overseen ByVarun Monga, MD

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Varun Monga, MD

No Placebo Group

Breakthrough Therapy

Trial Summary

What is the purpose of this trial?This trial tests a new device that creates magnetic and electric fields, used while patients sleep. It targets adults whose brain cancer has returned after initial treatment. The device is combined with standard chemotherapy to see if it helps fight the cancer more effectively. The approach aims to suppress the growth of cancer cells.

Eligibility Criteria

Participant Groups

2Treatment groups

Experimental Treatment

Group I: Patients: sBE device applied during sleep, in combination with Lomustine and BevacizumabExperimental Treatment3 Interventions

The sBE device is to be used 8 hours a day by the patients, during sleep, for 8 weeks, while also receiving standard chemotherapy Lomustine and Bevacizumab

Group II: Partners of Patients (who sleep in same bed): sBEExperimental Treatment1 Intervention

Up to 12 associated unaffected partners may agree to sleep within the investigational sBE device congruent with the period of exposure of their rGBM partner (8 weeks + possible extension)