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Behavioural Intervention

Sleep Deprivation for Heart Function During Exercise

N/A

Recruiting

Led By Philip Millar, PhD

Research Sponsored by University of Guelph

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

No prescription of chronic medications other than oral contraceptives

Free of known cardiovascular or metabolic diseases or sleep disorders

Must not have

Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders

Timeline

Screening 3 weeks

Treatment Varies

Follow Up comparison between normal sleep and partial sleep deprivation, ~3 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to understand how lack of sleep affects blood pressure and heart function during exercise in young, healthy adults. The study will also look at sex differences. Participants will visit the lab after a night

Who is the study for?

This trial is for young, healthy adults interested in how lack of sleep affects heart function during exercise. Participants will need to visit the lab after both a normal night's sleep and a night with less sleep, keep track of their sleep and eating habits, and do cycling exercises.

What is being tested?

The study aims to see if not getting enough sleep leads to lower blood pressure because of reduced heart output when exercising. It also looks at whether men and women react differently to this kind of stress.

What are the potential side effects?

There are no direct side effects mentioned for participating in this trial since it involves natural behaviors like sleeping and exercising. However, participants may experience tiredness due to partial sleep deprivation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am not on any chronic medications except for oral contraceptives.

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I do not have any heart, metabolic diseases, or sleep disorders.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have been diagnosed with a heart, metabolic disease, or sleep disorder.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ comparison between normal sleep and partial sleep deprivation, ~3 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~comparison between normal sleep and partial sleep deprivation, ~3 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and comparison between normal sleep and partial sleep deprivation, ~3 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

cardiac output responses to cycling exercise

Secondary study objectives

Blood pressure responses to cycling exercise

Plasma volume

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Partial sleep deprivationExperimental Treatment1 Intervention

During this arm, participants will be asked to come to the lab for testing after a night of partial sleep deprivation. Participants will be asked to fall asleep at their habitual bedtime but wake up early (\~40% of normal sleep duration).

Group II: Normal sleepActive Control1 Intervention

During this arm, participants will be asked to come to the lab for testing after a night of normal sleep. Normal sleep will be defined as participants habitual sleep-wake timing.

0 / 3Eligibility criteria met