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Learning Strategies for Naming in Aphasia

Phase 2

Recruiting

Led By William Evans, PhD

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Must not have

Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.

History of other acquired or progressive neurological disease.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up initial assessment (pre-treatment), multiple timepoints up to 6-months post-treatment.

Awards & highlights

No Placebo-Only Group

Summary

This trial looks at new treatments to improve language skills for those with aphasia, a disorder caused by stroke or brain injury, & help them use them in everyday life.

Who is the study for?

This trial is for people who have had a stroke at least 6 months ago, resulting in chronic aphasia, which is difficulty with language and naming things. They must struggle on certain parts of a language test but can't have severe comprehension issues or other neurological diseases, unmanaged substance dependence, or serious mood disorders.

What is being tested?

The study tests three ways to help people with aphasia improve their ability to name pictures and use these skills in daily life. It compares treatments that focus on maximum effort, balance between effort and accuracy, and maximum accuracy using speeded naming tasks.

What are the potential side effects?

Since this trial involves non-medical interventions focused on learning strategies rather than drugs or surgery, traditional side effects are not expected. Participants may experience fatigue or frustration during the learning tasks.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have a severe mood or behavioral disorder that needs special mental health care.

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I have a history of a progressive neurological condition.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ initial assessment (pre-treatment), multiple timepoints up to 6-months post-treatment.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~initial assessment (pre-treatment), multiple timepoints up to 6-months post-treatment.

This trial's timeline: 3 weeks for screening, Varies for treatment, and initial assessment (pre-treatment), multiple timepoints up to 6-months post-treatment. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in correct responses in Confrontation Naming of Treated and Untreated Pictured Objects

Change in correct responses in Context Generalization of Treated and Untreated Pictured Objects

Secondary study objectives

Change in core lexicon analysis on the Aphasia Bank Discourse Protocol

Change in mean scores on the Aphasia Communication Outcome Measure Short-Form

Mean score on the Cactus and Camels Test (CCT)

+4 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

6Treatment groups

Experimental Treatment

Group I: Effort-maximized, then effort-accuracy balanced, then accuracy-maximizedExperimental Treatment3 Interventions