← Back to Search

Gait Training for Stroke

N/A
Recruiting
Led By Wen Liu, PhD
Research Sponsored by University of Kansas Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Independent ambulation before stroke
Must be after the first stroke
Timeline
Screening 3 weeks
Treatment Varies
Follow Up all participants will be assessed at baseline (during the evaluation) and at the end of the 8-week intervention.
Awards & highlights

Study Summary

This trial aims to see if a walking training program can improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a cycling exercise. Participants will walk on a treadmill with support and a special

Who is the study for?
This trial is for chronic stroke survivors who currently cannot walk. It's designed to help them develop a walking exercise program. To join, participants must have had a stroke that resulted in limited mobility and difficulty with walking.Check my eligibility
What is being tested?
The study is testing whether gait training using a treadmill and partial body-weight support can improve cardiovascular health more effectively than leg cycling exercises. Researchers will measure heart rate, blood pressure, and A1c levels to assess improvements.See study design
What are the potential side effects?
Potential side effects may include muscle soreness or fatigue due to the physical nature of the exercises. There might also be an increased risk of falls during gait training for those with severe balance issues.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I was able to walk on my own before having a stroke.
Select...
I have had a stroke before.
Select...
I cannot walk on my own.
Select...
I am between 18 and 80 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~all participants will be assessed at baseline (during the evaluation) and at the end of the 8-week intervention.
This trial's timeline: 3 weeks for screening, Varies for treatment, and all participants will be assessed at baseline (during the evaluation) and at the end of the 8-week intervention. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
changes in resting heart rate (rHR)
glycated hemoglobin (HbA1c)
systolic blood pressure (SBP)
Secondary outcome measures
changes in Berg Balance Scale (BBS) score
changes in cardiac output (CO)
changes in diastolic blood pressure (DBP)
+8 more
Other outcome measures
BMI, Body Mass Index
MoCA, Montreal Cognitive Assessment
changes in HADS, Hospital Anxiety and Depression Scale
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Gait TrainingExperimental Treatment1 Intervention
The gait training in the experimental group will use a treadmill with a partial body-weight support system and our gait training device. A gait training session will include 2-minute warming up at the beginning and 2-minute cooling down at the end, at a treadmill speed of 0.6 mph. After the warming up, the treadmill speed will increase at every two minutes by an increment of 0.2 mph. Participant's heart rate will be monitored throughout the training session by using a Polar OH1 optical HR sensor placed in the participant's left forearm. Reseachers will stop the increase and maintain the same treadmill speed after the HR reaching the target heart rate zone of 50% - 60% of age-predicted heart rate reserve.
Group II: Leg Cycling ExerciseActive Control1 Intervention
The leg cycling exercise will use a stationary bicycle and the similar protocol as in the experimental group. The cycling exercise will include 2-minute warming up in the beginning and 2-minute cooling down at the end with a speed of 10 rpm and resistance of level 1 of 4. After warming up, the speed will increase at every two minutes by an increment of 5 rpm until reaching the target heart rate zone of 50% - 60% of age-predicted maximum heart rate. If the participant cannot tolerate any more increase in cycling speed before reaching the target heart rate, the resistance will be increased. The training duration will be individualized at the beginning and increase weekly by 5 minutes, depending on the tolerance of the participant, up to the maximum of 30 minutes. Both heart rate and blood pressure will be monitored before, during, and after each session to ensure safety. Each session including setting up will be about one hour.

Find a Location

Who is running the clinical trial?

University of Kansas Medical CenterLead Sponsor
470 Previous Clinical Trials
171,350 Total Patients Enrolled
8 Trials studying Stroke
611 Patients Enrolled for Stroke
Wen Liu, PhDPrincipal InvestigatorUniversity of Kansas Medical Center
6 Previous Clinical Trials
204 Total Patients Enrolled
1 Trials studying Stroke
20 Patients Enrolled for Stroke
~48 spots leftby Sep 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top