~0 spots leftby Apr 2026

Navigated Transcranial Magnetic Stimulation in Monitoring Stroke Recovery

Recruiting in Palo Alto (17 mi)
Overseen byKari Dunning, PhD,PT
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Nexstim Ltd
No Placebo Group

Trial Summary

What is the purpose of this trial?

The past 10 years of research in persons more than 6 months post stroke have shown certain types of rehabilitation can help "re-wire" the brain. Transcranial magnetic stimulation (TMS) can be used to monitor this re-wiring by mapping the brain's function (measuring brain activity). Recent research suggests that TMS can be used for both prognosis (determining future function) and to determine what type of rehabilitation therapy will work best after stroke. The purposes of this research study are to: 1) determine changes in brain activity during the first 6 months after stroke (to determine how the brain "re-wires"); 2) compare changes in recovery of motor function with changes in brain re-wiring; 3) determine the ability of TMS to "predict" functional outcome in the first 6 months after stroke. The primary hypotheses are: 1) functional recovery will be correlated with TMS changes (as measure motor threshold (MT), motor evoked potentials (MEPs) and recruitment curves; 2) baseline TMS will predict future functional outcomes at 3 and 6 months.

Eligibility Criteria

Inclusion Criteria

one sided ischemic stroke confirmed by radiology
20-80 years old

Treatment Details

Interventions

  • Navigated TMS examination (Other)
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Navigated TMSExperimental Treatment1 Intervention
single arm study where all subjects will be studied using the Navigated TMS device

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
Drake Rehabilitation CenterCincinnati, OH
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Who Is Running the Clinical Trial?

Nexstim LtdLead Sponsor

References