Trial Summary
What is the purpose of this trial?Almonds are a good source of beneficial compounds. This study will investigate if eating almonds everyday for 12 weeks can affect gut health and inflammation in persons with metabolic syndrome. Investigators will measure changes in metabolism, heart health, and the levels of vitamins and other compounds from almonds.
Eligibility Criteria
Adults aged 35-60 with metabolic syndrome, willing to eat almonds daily and avoid other nuts, probiotics, multivitamins, and certain supplements for 13 weeks. Participants should have hypertension, high blood sugar, central obesity or abnormal cholesterol levels but no allergies to nuts/wheat/gluten, heavy alcohol use, recent tobacco use or antibiotic intake.Inclusion Criteria
Willing to maintain current eating patterns (no significant diet change during study)
I am willing to stop taking probiotic supplements for the study duration.
I am willing to stop taking certain vitamins and supplements for 13 weeks.
+4 more
Exclusion Criteria
I have not used tobacco or smoked any substance in the last 3 months.
I have had weight loss surgery or have a chronic digestive condition.
I have been diagnosed with hemochromatosis.
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Participant Groups
The trial is testing if consuming almonds every day for 12 weeks can improve gut health and reduce inflammation in people with metabolic syndrome. The effects on metabolism and heart health will be monitored along with the impact of almond-derived nutrients.
2Treatment groups
Active Control
Placebo Group
Group I: AlmondsActive Control1 Intervention
Daily consumption of 2 ounces of unsalted, dry roasted almonds for 12 weeks
Group II: CrackersPlacebo Group1 Intervention
Daily consumption of non-whole grain crackers for 12 weeks (caloric equivalent to 2 ounces of dry roasted almonds)
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Oregon State UniversityCorvallis, OR
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Who Is Running the Clinical Trial?
Oregon State UniversityLead Sponsor