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Prebiotic

Prebiotics for Ulcerative Colitis

N/A
Recruiting
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ages 18 to 85 years old
History of biopsy-proven ulcerative colitis (UC)
Must not have
Urgent need for abdominal surgery
Prior colectomy
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 16
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to understand the effects of prebiotics on gut health in patients with inflammatory bowel disease (IBD). Participants will be given prebiotic supplements for 8 weeks and their dietary habits

Who is the study for?
This trial is for individuals with Ulcerative Colitis or other forms of Inflammatory Bowel Disease. Participants should be interested in how diet affects their condition and willing to take prebiotic supplements. They'll need to provide stool samples and dietary information regularly.
What is being tested?
The study tests the effects of prebiotics on gut health over 16 weeks. Participants will start taking a prebiotic supplement either immediately or after an initial 8-week period, to see if it changes the gut microbiome and improves symptoms.
What are the potential side effects?
Prebiotics are generally considered safe but may cause digestive discomfort such as bloating, gas, or altered bowel habits as the body adjusts to increased fiber intake.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 85 years old.
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I have been diagnosed with ulcerative colitis through a biopsy.
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I am experiencing noticeable symptoms from my condition.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I need urgent surgery in my abdomen.
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I have had my colon surgically removed.
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I do not have any unstable major medical conditions.
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I am currently receiving treatment for cancer.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 16
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 16 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Secondary study objectives
Clinical remission
Clinical response
Microbial composition

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Prebiotic at Week 0Experimental Treatment1 Intervention
Group II: Prebiotic at Week 8Active Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Prebiotic
2016
Completed Phase 2
~800

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,568 Previous Clinical Trials
10,314,202 Total Patients Enrolled
~47 spots leftby Dec 2026