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Behavioral Intervention

Single Session Psychotherapy for Depression (CARED Trial)

N/A
Waitlist Available
Led By Flavio Frohlich, Ph.D.
Research Sponsored by University of North Carolina, Chapel Hill
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnostic and Statistical Manual (DSM)-5 diagnosis of major depressive disorder (MDD) as confirmed by semi-structured clinical assessment
Age of 18 years or older
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and two weeks post-intervention
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to see if a single session intervention can help reduce psychological issues in adults with moderate depression. They want to know if this intervention is acceptable to participants, if it can be done in one

Who is the study for?
This trial is for adults with moderate to severe depression. Participants must complete a detailed diagnostic interview, mental health questionnaires at the start and two weeks after treatment, and attend a 3-hour single session of psychotherapy.
What is being tested?
The study tests if a one-time psychotherapeutic intervention can lessen psychological distress in those with depression. It evaluates the acceptability and feasibility of this approach, as well as its effectiveness in reducing symptoms.
What are the potential side effects?
Since this is a psychotherapy intervention, there may not be physical side effects like with medication. However, discussing difficult emotions could temporarily increase distress or discomfort.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been diagnosed with major depressive disorder.
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I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and two weeks post-intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and two weeks post-intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
CARED Treatment Experience Survey
Secondary study objectives
Change from baseline on Becks Depression Inventory II at two weeks post-intervention
Change from baseline on Behavioral Activation Scale at two weeks post-intervention
Change from baseline on Behavioral Inhibition and Behavioral Activation Scale - Activation Drive Subscale at two weeks post-intervention
+11 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Psychotherapy ArmExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

The Foundation of Hope for Research and Treatment of Mental IllnessUNKNOWN
2 Previous Clinical Trials
32 Total Patients Enrolled
University of North Carolina, Chapel HillLead Sponsor
1,561 Previous Clinical Trials
4,298,726 Total Patients Enrolled
Flavio Frohlich, Ph.D.Principal InvestigatorUniveristy of North Carolina Chapel Hill
~10 spots leftby Mar 2025
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