Single Session Psychotherapy for Depression
(CARED Trial)

Recruiting in Palo Alto (17 mi)

Overseen byFlavio Frohlich, Ph.D.

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of North Carolina, Chapel Hill

No Placebo Group

Trial Summary

What is the purpose of this trial?The goal of this clinical trial is to learn whether an single session intervention can reduce psychological impairment in adult individuals with moderate depression. The main questions it aims to answer are: Is this evidence-based intervention acceptable to study participants? Is this evidence-based intervention feasible to implement in a single session? Is there evidence that the evidence-based intervention reduces psychological impairment in adults with moderate to severe depression? Participants will complete: * an in-depth diagnostic screening interview prior to enrollment * a set of mental health questionnaires at baseline and two weeks post-intervention * a 3-hour, evidence-based, single session psychotherapeutic intervention with a trained clinician

Eligibility Criteria

This trial is for adults with moderate to severe depression. Participants must complete a detailed diagnostic interview, mental health questionnaires at the start and two weeks after treatment, and attend a 3-hour single session of psychotherapy.

Inclusion Criteria

Speak and understand English

Able to provide informed consent

I am willing and able to follow the study rules and attend all appointments.

+3 more

Exclusion Criteria

I have not had brain surgery before.

Participants must not meet criteria for current severe substance use disorder, anorexia nervosa, or active psychosis as assessed by psychodiagnostic assessment

Participants must not have current active suicide intent as determined by the Columbia Suicide Severity Rating Scale (C-SSRS)

+6 more

Participant Groups

The study tests if a one-time psychotherapeutic intervention can lessen psychological distress in those with depression. It evaluates the acceptability and feasibility of this approach, as well as its effectiveness in reducing symptoms.

1Treatment groups

Experimental Treatment

Group I: Psychotherapy ArmExperimental Treatment1 Intervention