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Exercise Training for Mental Illness
N/A
Recruiting
Led By Ryan Garten, PhD
Research Sponsored by Virginia Commonwealth University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Apparently healthy and free of overt cardiovascular, pulmonary, or metabolic disease
Be between 18 and 65 years old
Must not have
Taking medications that could influence cardiovascular function
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to the end of the final visit, about 14 weeks
Awards & highlights
No Placebo-Only Group
Summary
This trial will test the effects of different types of exercise on blood vessel function in people with and without mental health disorders.
Who is the study for?
This trial is for healthy individuals and those with PTSD or GAD who have specific scores on mental health scales. It's not for pregnant women, current/recent smokers, people with limited English proficiency, those on certain cardiovascular meds, drug/alcohol users, or anyone on a significant calorie restriction.
What is being tested?
The study is testing the effects of two types of exercise training—muscular fitness and strength training—on blood vessel function in both healthy participants and those with PTSD or GAD.
What are the potential side effects?
While the trial involves exercise interventions that are generally safe, potential side effects may include muscle soreness, fatigue, joint pain or injury from physical activity.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am healthy with no obvious heart, lung, or metabolic diseases.
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I am on medication that affects my heart's health.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline to the end of the final visit, about 14 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to the end of the final visit, about 14 weeks
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Arm Vascular Function at Rest (Flow Mediated Dilation Test)
Arm Vascular Function in Response to Exercise (Handgrip Exercise Test)
Leg Vascular Function (Passive Leg Movement Test)
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Group I: Muscular fitnessExperimental Treatment1 Intervention
Participants will complete study 1 (HM20020955-1) and then 10 weeks of resistance training for muscular fitness
Group II: Muscular StrengthExperimental Treatment1 Intervention
Participants will complete study 1 (HM20020955-1) and then 10 weeks of resistance training for muscular strength
Find a Location
Who is running the clinical trial?
Virginia Commonwealth UniversityLead Sponsor
719 Previous Clinical Trials
22,895,596 Total Patients Enrolled
Ryan Garten, PhDPrincipal InvestigatorVirginia Commonwealth University
5 Previous Clinical Trials
1,187 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You are using illegal drugs or drinking too much alcohol.I have recently quit smoking.I am on medication that affects my heart's health.For the GAD group, your score on the GAD-7 self-report scale should be 10 or higher, and your score on the PCL-5 checklist should be less than 33.You have been significantly restricting your calorie intake or have vitamin/mineral deficiencies.Healthy participants should have low scores on the GAD-7 and PCL-5 questionnaires.I am healthy with no obvious heart, lung, or metabolic diseases.You have a score of 33 or higher on the PCL-5 checklist for PTSD.