Glioblastoma Clinical Trials in Raleigh, NC

View the best 10 glioblastoma medical studies in Raleigh, North Carolina. Access promising new therapies by applying to a Raleigh-based Glioblastoma clinical trial.

Trials in Raleigh, North Carolina

Here are the top 10 medical studies for glioblastoma in Raleigh, North Carolina

Dichloroacetate (DCA)

Metabolic Modulator

Recruiting1 awardPhase 2

This trial tests if DCA, a medication taken by mouth, can help treat patients with returning brain tumors who are scheduled for surgery. DCA may change how tumor cells use energy, potentially slowing their growth. DCA has shown potential activity against several human cancers, including brain tumors.

Everolimus +1 More

mTOR Inhibitor

Recruiting1 awardPhase 2

This trial is testing whether the combination of ribociclib and everolimus can help children and young adults with aggressive brain tumors live longer. Everolimus is a medication that has been approved for treating various cancers. These drugs are taken by mouth and work by stopping cancer cells from growing. The study focuses on patients whose tumors have specific genetic changes that make them hard to treat with standard therapies.

IGV-001 +2 More

Cell Immunotherapy

Recruiting0 awardsPhase 2

This trial will compare a new treatment for glioblastoma to placebo to see if it extends survival.

Ropidoxuridine

Radiosensitizer

Recruiting1 awardPhase 2

"This trial is testing a drug called ropidoxuridine to see if it can make radiation therapy more effective in patients with a specific type of brain cancer. The study will look at how safe and

VAL-083 +7 More

Alkylating agents

Recruiting1 awardPhase 2 & 3

This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.

ST101

Virus Therapy

Recruiting1 awardPhase 1 & 2

This trial tests a new drug, ST101, given to patients with advanced cancers who haven't responded to other treatments. The study aims to find the safest and most effective dose. It includes patients with specific types of breast cancer, melanoma, brain cancer, and prostate cancer.

CAR.B7-H3T cells

CAR T-cell Therapy

Recruiting1 awardPhase 1

This trial is testing if it's safe to use CAR.B7-H3T cells, a treatment for glioblastoma that hasn't been tested on humans before.

Atezolizumab

Checkpoint Inhibitor

Recruiting1 awardPhase 2

"This trial aims to see if giving atezolizumab before surgery can help patients with recurrent glioblastoma and low mutational burden."

GammaTile radiation therapy implantation +3 More

Brachytherapy

Recruiting3 awardsPhase 4

This trial tests if adding GammaTile radiation therapy to standard treatment can improve outcomes for patients with newly diagnosed GBM. GammaTile delivers quick, direct radiation to the tumor, which may help control the tumor better and improve survival rates.

Selinexor +1 More

Selective Inhibitor of Nuclear Export

Recruiting1 awardPhase 1 & 2

This trial tests selinexor with temozolomide for patients whose brain cancer has returned. Selinexor blocks a protein that helps cancer cells grow, and temozolomide damages their DNA to kill them or stop their growth. Temozolomide is a DNA methylating drug currently used as a first-line treatment in glioblastoma therapy.

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Trials With No Placebo

mTOR Inhibitor

Ribociclib + Everolimus for Brain Tumors

Recruiting1 awardPhase 2

Durham, North Carolina

This trial is testing whether the combination of ribociclib and everolimus can help children and young adults with aggressive brain tumors live longer. Everolimus is a medication that has been approved for treating various cancers. These drugs are taken by mouth and work by stopping cancer cells from growing. The study focuses on patients whose tumors have specific genetic changes that make them hard to treat with standard therapies.

Brachytherapy

GammaTile + Stupp Protocol for Glioblastoma

Recruiting3 awardsPhase 4

Greenville, North Carolina

This trial tests if adding GammaTile radiation therapy to standard treatment can improve outcomes for patients with newly diagnosed GBM. GammaTile delivers quick, direct radiation to the tumor, which may help control the tumor better and improve survival rates.

Alkylating agents

Multiple Therapies for Glioblastoma

Recruiting1 awardPhase 2 & 3

Durham, North Carolina

This trial is testing various treatments for patients with newly diagnosed or returning brain cancer. It adjusts treatments based on how well patients are doing to find the most effective options. The goal is to improve survival rates by matching the best treatments to specific patient types.

Radiation

Dabrafenib + Trametinib After Radiation for Brain Cancer

Recruiting1 awardPhase 2

Winston-Salem, North Carolina

This trial studies how well dabrafenib and trametinib work after radiation therapy in children and young adults with a specific type of brain tumor. These drugs help stop tumor growth by blocking signals that tell the cells to multiply. Dabrafenib has been developed and tested extensively for a specific type of skin cancer, showing effectiveness both alone and when used with trametinib.

PARP Inhibitor

PARP Inhibitor + Temozolomide for Brain Cancer

Recruiting1 awardPhase 1

Durham, North Carolina

This trial studies the safety and best dose of BGB-290 and temozolomide in treating young people with a specific type of brain tumor. BGB-290 blocks enzymes needed for tumor growth, while temozolomide kills or stops cancer cells from growing. The goal is to find out if this combination works better for these patients.

Alkylating Agent

Veliparib + Radiation + Temozolomide for Brain Cancer

Recruiting1 awardPhase 2

Chapel Hill, North Carolina

This trial is studying a combination of drugs as a potential treatment for newly diagnosed malignant glioma. The drugs being studied are veliparib, radiation therapy, and temozolomide.

Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.