Popular Trials
Vaccine
Influenza Vaccine for Infertility
This trial is testing if a flu shot can help women undergoing IVF get pregnant. The study focuses on women who have had trouble with miscarriages or embryo implantation. Researchers think the flu shot might make the immune system more supportive of pregnancy.
Ovarian Reserve Testing for Infertility in Cancer Survivors
This trial is testing if two measures of ovarian reserve - blood draws and pelvic ultrasounds - can accurately predict if a young adult cancer survivor will experience a return of menses. The trial will also compare the results of the ovarian reserve measures between cancer survivors and healthy controls, and between cancer survivors taking and not taking combined estrogen and progesterone hormone products.
Behavioral Intervention
Self-Help Program for Emotional Distress Due to Infertility
This trial is researching a 7-week program to reduce distress for women struggling with infertility. Results will help make the program widely available to improve mental health and well-being for women with infertility.
Popular Filters
Trials for Female Infertility Patients
Behavioral Intervention
Mindset Management for Stress in Women With Infertility
This trial aims to see if a mindset management program called Organic Conceptions can reduce stress levels in women with infertility. Participants will be divided into two groups, with one group receiving the program and the other
Trials for Male Infertility Patients
Selective Serotonin Reuptake Inhibitor
Escitalopram for Sperm DNA Fragmentation
This trial is testing the effects of escitalopram, a common antidepressant, on healthy men with normal fertility and no history of mental health issues. Researchers want to see if this medication affects sperm quality and overall fertility. The results will help doctors advise men who are concerned about fertility and are taking or considering taking escitalopram.
Procedure
ROSI for Male Infertility
This trial is testing a procedure that uses immature sperm cells to help men who can't produce mature sperm have biological children. The process involves selecting these cells and injecting them into an egg, with extra steps to ensure the egg is ready to develop. This technique has been explored as an alternative for men who cannot produce mature sperm.
Fertility Preservation Discussion for Cancer
This trial is testing whether having a guided conversation about fertility preservation with an expert increases the rates of fertility preservation and/or satisfaction with the decision among adolescent and young adult males with cancer.
Device
Home Semen Testing for Male Infertility
This trial is looking to see if home semen testing is a feasible and useful way to screen for male factor infertility. They will also be looking at the impact that home semen testing has on fertility-related quality of life and whether or not it increases the diagnosis and treatment of male infertility.
Procedure
Platelet Rich Plasma Treatment for Male Infertility
This trial is testing whether injecting a special substance made from a patient's own blood into their testicles can help men who couldn't retrieve sperm in a previous procedure. The goal is to see if this treatment can improve their chances of having children through medical procedures.
Dietary Supplement
Prenatal Supplements for Male Infertility
This trial tests if a few months of taking the 'Power Prenatal for Sperm' supplement can improve sperm quality in men with infertility issues. The supplement contains nutrients that may help improve sperm concentration, movement, and shape.
Phase 3 Trials
Selective Estrogen Receptor Modulator
Tamoxifen + Letrozole for Fertility Preservation in Breast Cancer
This trial is testing two medication combinations to help women with breast cancer preserve their fertility. It focuses on women with a specific type of breast cancer and aims to find out which combination helps produce more mature eggs. The medications work by managing hormone levels and stimulating the ovaries. Tamoxifen and letrozole have been used to safely manage hormone levels in breast cancer patients undergoing fertility preservation.
Polyphenol
Fibroids & Infertility
This trial tests if a low caffeine green tea extract with high EGCG can help women aged 18-40 with fibroids get pregnant. The EGCG may shrink fibroids and improve the uterus lining, increasing pregnancy chances. EGCG, a major component of green tea, has been studied for its potential benefits in reducing uterine fibroids and improving reproductive health.
Trials With No Placebo
Genetic Testing
niPGT-A for Infertility
This trial tests a new, non-invasive method to check embryos for chromosomal issues by analyzing DNA in the culture medium. It aims to help IVF patients who prefer not to use invasive testing. The goal is to improve pregnancy rates by selecting the healthiest embryos without needing invasive procedures. This method emerged from the discovery of embryonic DNA in spent embryo culture medium.
Selective Estrogen Receptor Modulator
Tamoxifen + Letrozole for Fertility Preservation in Breast Cancer
This trial is testing two medication combinations to help women with breast cancer preserve their fertility. It focuses on women with a specific type of breast cancer and aims to find out which combination helps produce more mature eggs. The medications work by managing hormone levels and stimulating the ovaries. Tamoxifen and letrozole have been used to safely manage hormone levels in breast cancer patients undergoing fertility preservation.
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Frequently Asked Questions
Introduction to infertility
What are the top hospitals conducting infertility research?
Infertility can be a challenging and emotional journey for many couples, but there is hope in the form of clinical trials conducted by top hospitals around the world. In Regina, Canada, the University of Regina is making strides with four active infertility trials. Although they may have a smaller number of all-time trials (four), their commitment to researching and finding solutions for this condition is evident since recording their first trial in 2021.
Meanwhile, Boston IVF in Waltham has been at the forefront of infertility research since 1999 when they initiated their inaugural trial. With three ongoing infertility trials and an impressive history of 23 completed studies, this institution exemplifies dedication to understanding and addressing fertility challenges.
In New york City, Weill Cornell Medicine joins the ranks with three active infertility trials. Since conducting their first trial in 2012, they have made significant contributions to advancing our knowledge regarding fertility issues through six previously conducted investigations.
Further south in Clearwater, Florida's Women's Medical Research Group holds two current infertility trials while having accomplished six earlier studies dating back to their pioneering investigation on such cases starting from2008.Located outside Philadelphia, Main Line Fertility also plays a pivotal role with two ongoing clinical tests as well as contributing towards paving new paths through five previous investigations; theirs are traced back only seven years ago until2014.
These hospitals stand as beacons of hope for individuals struggling with infertility. Their relentless pursuit of knowledge and innovative treatment options brings us closer to fulfilling dreams of parenthood worldwide while reminding us that no obstacle is insurmountable when faced with passion-driven medical advancements
Which are the best cities for infertility clinical trials?
When it comes to infertility clinical trials, several cities stand out as hubs of research and innovation. In New york, there are currently 10 active trials focusing on treatments like sperm sorting, gamete treatment, and in vitro maturation. Chicago follows closely with 7 ongoing studies exploring the potential benefits of interventions such as green tea extract and Elagolix 200 MG. Philadelphia also shows promise with 6 active trials investigating approaches like femaSeed localized directional insemination and programmed cycles. Other notable cities include Oklahoma City with 5 active trials studying similar techniques, and San Francisco with its own set of 5 ongoing investigations into promising methods like ZP bound sperm selection oocyte cohort. These dedicated research efforts offer hope for individuals struggling with infertility by advancing our understanding and expanding treatment options.
Which are the top treatments for infertility being explored in clinical trials?
Exciting advancements in infertility treatments are taking place through various clinical trials. Uterine transplant, a groundbreaking procedure, is currently being explored in three active trials dedicated to addressing infertility. Its first listing dates back to 2015 and it has been involved in four all-time infertility trials. Another innovative approach is sperm sorting, which has shown promise with one ongoing trial since its introduction in 2013. Additionally, automated sperm selection software offers a potential solution and is currently under investigation in one active trial after being listed for the first time in 2021. These cutting-edge developments hold great potential for individuals struggling with infertility as researchers strive to expand treatment options and bring hope into their lives.
What are the most recent clinical trials for infertility?
Recent clinical trials offer promising advancements in the field of infertility, providing hope for individuals struggling to conceive. One notable trial examines the efficacy of kisspeptin and GnRH in addressing infertility concerns. Another significant study focuses on uterus transplant recipients, aiming to expand our understanding of this innovative procedure's impact on fertility. Additionally, researchers are investigating the potential benefits of green tea extract as a treatment option for infertility. Furthermore, Endometrin 100 mg three times per day (TID) is being studied for its effectiveness in enhancing fertility outcomes. These ongoing trials demonstrate the relentless pursuit towards finding effective solutions for couples facing challenges with conception.
What infertility clinical trials were recently completed?
Recently, several significant clinical trials have concluded, contributing valuable insights into the field of infertility treatment. In July 2022, American Genomics conducted a trial on AG-920 to address this pressing issue. Furthermore, Stanford University completed a trial in August 2017 exploring Uterine ERA and microbiome testing. Finally, Letrozole was investigated by Weill Medical College of Cornell University in November 2009 as a potential therapy for infertility. These studies exemplify the ongoing efforts to advance medical knowledge and provide hope for couples struggling with infertility.