Sepsis Clinical Trials 2024

What are the top hospitals conducting sepsis research?

In the battle against sepsis, several top hospitals are leading the charge with their commitment to groundbreaking clinical trials. In Philadelphia, the Children's Hospital of Philadelphia is at the forefront, currently conducting four active sepsis trials and boasting a total of seven completed trials in this field. Since recording its first trial in 2013, this hospital has been dedicated to advancing our understanding and treatment of sepsis. The University of Minnesota in Minneapolis also takes center stage, with four ongoing sepsis trials and an all-time tally of four trials as well. Although relatively new to the field compared to other institutions, having started their first recorded trial just last year in 2022, they have made significant strides.

Meanwhile, Washington University in Saint Louis joins these ranks by actively conducting four sepsis trials while maintaining a record of seven completed studies since initiating their inaugural trial in 2020. Similarly contributing towards better comprehension and management of this condition is Nationwide Children's Hospital located in Columbus; it is presently involved with four active clinical tests along with previously holding records for another quartet starting from way back into late 2018.

Lastly but equally important comes Children's Hospital Pittsburgh situated within Pennsylvania state that keeps itself equal pace presenting its full devotion through similar counts including up-to-date involvement via those same running number -four ongoing research projects- after initially stepping ground on such endeavors during 2018

These esteemed hospitals play a vital role not only by providing hope for those affected by sepsis but also by pushing boundaries and striving for improved outcomes and treatments worldwide. With each trial conducted at these leading medical centers comes valuable insights that contribute to saving lives amidst the challenging landscape presented by this severe condition

Which are the best cities for sepsis clinical trials?

Pittsburgh, Pennsylvania; Philadelphia, Pennsylvania; and Boston, Massachusetts are three prominent cities for sepsis clinical trials. Pittsburgh leads the way with 11 ongoing studies focused on treatments like GM-CSF, IV Acetaminophen-Active, and Low-intensity Remote Patient Monitoring (RPM) + Enhanced Team. Philadelphia follows closely behind with 10 active trials exploring interventions such as GM-CSF and Empiric antibiotics. In addition, Boston also has 10 active trials investigating therapies like Inhaled Carbon Monoxide at CFK equation-determined personalized dose and IV Acetaminophen-Active. These cities offer individuals battling sepsis access to cutting-edge clinical trials that contribute to advancements in care and potentially improve patient outcomes.

Which are the top treatments for sepsis being explored in clinical trials?

Sepsis, a life-threatening condition, is the focus of ongoing clinical trials exploring innovative treatment options. GM-CSF stands out at the forefront with two active trials and three all-time sepsis trials since its introduction in 2011. Another promising avenue being explored is sepsis education, currently undergoing one active trial and boasting one all-time sepsis trial since its listing in 2014. These research endeavors hold immense potential to enhance our understanding of sepsis management and pave the way for improved patient outcomes.

What are the most recent clinical trials for sepsis?

Promising advancements in sepsis research have led to several recent clinical trials that hold great potential for improving patient outcomes. One such trial focuses on the use of gentamicin-based irrigation, which aims to combat sepsis through targeted delivery of antibiotics directly to the affected areas. Additionally, fisetin at a specific dosage has shown promise in treating sepsis and reducing its detrimental effects. Another significant development is the investigation of ceftobiprole as a treatment option for sepsis patients in Phase 3 trials—an important step towards validating its efficacy and safety. Moreover, personalized doses of inhaled carbon monoxide are being explored to establish optimal levels for combating sepsis complications effectively. Lastly, xylitol is under scrutiny as a potential intervention in managing sepsis symptoms and enhancing overall recovery rates among patients involved in Phase 2 studies.

What sepsis clinical trials were recently completed?

Recently, two important clinical trials focusing on sepsis reached completion. In January 2021, Joseph L. Kuti, PharmD sponsored a trial investigating the potential of Imipenem, Cilastatin and Relebactam in combatting this life-threatening condition. Additionally, Beth Israel Deaconess Medical Center concluded their study on Thiamine Hydrochloride back in September 2018. These trials shed light on innovative approaches to addressing sepsis and contribute to advancing our understanding of effective treatment strategies for this critical medical challenge.