Butenafine Hydrochloride

Tinea Pedis, Tinea Versicolor, Tinea Cruris + 1 more

Treatment

0 Active Studies for Butenafine Hydrochloride

What is Butenafine Hydrochloride

Butenafine

The Generic name of this drug

Treatment Summary

Butenafine hydrochloride is a type of antifungal drug used to treat skin infections caused by certain types of fungi. It works by blocking the production of certain sterols that are required for fungal cell membranes. It targets a specific enzyme called squalene epoxidase that is essential for the formation of these sterols.

Lotrimin Ultra Antifungal

is the brand name

image of different drug pills on a surface

Butenafine Hydrochloride Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Lotrimin Ultra Antifungal

Butenafine

1993

22

Effectiveness

How Butenafine Hydrochloride Affects Patients

Butenafine is a medicine used to treat fungal infections. It is similar to other antifungal agents and works by disrupting the membranes of the fungus cells and preventing them from growing. Butenafine is especially effective against dermatophytes, a type of fungus that commonly affects the skin, nails, and hair. It is also effective against Candida albicans and other fungi, including Cryptococcus neoformans and Aspergillus spp.

How Butenafine Hydrochloride works in the body

Butenafine works by blocking an enzyme that creates a key molecule needed to make fungal cell membranes. This inhibits fungal growth and leads to the cell leaking its contents. Butenafine also causes a buildup of another molecule, called squalene, which is thought to directly kill fungal cells.

When to interrupt dosage

The advised dosage of Butenafine Hydrochloride is contingent upon the diagnosed condition, including Tinea Corporis, Tinea cruris and Tinea Pedis. The measure of medication can be found in the table below, based on the technique of delivery (e.g. Topical or Cream - Topical).

Condition

Dosage

Administration

Tinea Cruris

, 0.01 mg/mg, 1.0 %

Topical, , Cream, Cream - Topical

Tinea

, 0.01 mg/mg, 1.0 %

Topical, , Cream, Cream - Topical

Tinea Pedis

, 0.01 mg/mg, 1.0 %

Topical, , Cream, Cream - Topical

Tinea Versicolor

, 0.01 mg/mg, 1.0 %

Topical, , Cream, Cream - Topical

Butenafine Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Butenafine Hydrochloride?

Presently, there are no active trials examining the potential of Butenafine Hydrochloride in providing relief from Pityriasis versicolor, Tinea Corporis and Tinea Pedis.

Condition

Clinical Trials

Trial Phases

Tinea Cruris

0 Actively Recruiting

Tinea Versicolor

0 Actively Recruiting

Tinea

0 Actively Recruiting

Tinea Pedis

0 Actively Recruiting

Butenafine Hydrochloride Reviews: What are patients saying about Butenafine Hydrochloride?

4.7

Patient Review

12/22/2017

Butenafine Hydrochloride for Ringworm of Groin Area

I found that the best way to use this cream was to wash the area with warm water, dry it well, then apply the cream at night. Sleeping nude also helped ensure ventilation of the affected area.

3.7

Patient Review

1/31/2015

Butenafine Hydrochloride for Ringworm of Groin Area

2.3

Patient Review

5/2/2016

Butenafine Hydrochloride for Fungal Infection of the Skin with Yellow Patches

Clotrimazole cream cleared up my fungal infection within a day, but this treatment did nothing.

Patient Q&A Section about butenafine hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can you use butenafine hydrochloride on vagina?

"This medicine is only to be used on the skin and must not come into contact with the eyes, nose, mouth, or vagina."

Answered by AI

What is butenafine hydrochloride cream used for?

"This medicine is for fungus infections of the skin. It can treat tinea (pityriasis) versicolor caused by M. furfur. The medicine works by either killing the fungus or preventing its growth. You need a prescription from a doctor to get this medicine."

Answered by AI

Can I use butenafine hydrochloride twice a day?

"You can use Mentax more than once or twice a day depending on what the package recommends or your doctor prescribes."

Answered by AI

Which is better clotrimazole or butenafine hydrochloride?

"Butenafine was more effective than clotrimazole in curing athletes foot, with 61.7% of those using butenafine being cured compared to 17.6% of those using clotrimazole."

Answered by AI