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What is Butenafine Hydrochloride
ButenafineThe Generic name of this drug
Treatment SummaryButenafine hydrochloride is a type of antifungal drug used to treat skin infections caused by certain types of fungi. It works by blocking the production of certain sterols that are required for fungal cell membranes. It targets a specific enzyme called squalene epoxidase that is essential for the formation of these sterols.
Lotrimin Ultra Antifungalis the brand name
Butenafine Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lotrimin Ultra Antifungal
Butenafine
1993
22
Effectiveness
How Butenafine Hydrochloride Affects PatientsButenafine is a medicine used to treat fungal infections. It is similar to other antifungal agents and works by disrupting the membranes of the fungus cells and preventing them from growing. Butenafine is especially effective against dermatophytes, a type of fungus that commonly affects the skin, nails, and hair. It is also effective against Candida albicans and other fungi, including Cryptococcus neoformans and Aspergillus spp.
How Butenafine Hydrochloride works in the bodyButenafine works by blocking an enzyme that creates a key molecule needed to make fungal cell membranes. This inhibits fungal growth and leads to the cell leaking its contents. Butenafine also causes a buildup of another molecule, called squalene, which is thought to directly kill fungal cells.
When to interrupt dosage
The advised dosage of Butenafine Hydrochloride is contingent upon the diagnosed condition, including Tinea Corporis, Tinea cruris and Tinea Pedis. The measure of medication can be found in the table below, based on the technique of delivery (e.g. Topical or Cream - Topical).Condition
Dosage
Administration
Tinea cruris
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Tinea
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Tinea Pedis
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Tinea Versicolor
, 0.01 mg/mg, 1.0 %
, Topical, Cream, Cream - Topical
Butenafine Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Butenafine Hydrochloride?
Presently, there are no active trials examining the potential of Butenafine Hydrochloride in providing relief from Pityriasis versicolor, Tinea Corporis and Tinea Pedis.Condition
Clinical Trials
Trial Phases
Tinea cruris
0 Actively Recruiting
Tinea Versicolor
0 Actively Recruiting
Tinea
0 Actively Recruiting
Tinea Pedis
0 Actively Recruiting
Butenafine Hydrochloride Reviews: What are patients saying about Butenafine Hydrochloride?
4.7Patient Review
12/22/2017 I found that the best way to use this cream was to wash the area with warm water, dry it well, then apply the cream at night. Sleeping nude also helped ensure ventilation of the affected area.
3.7Patient Review
1/31/20152.3Patient Review
5/2/2016 Clotrimazole cream cleared up my fungal infection within a day, but this treatment did nothing.
Patient Q&A Section about butenafine hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can you use butenafine hydrochloride on vagina?
"This medicine is only to be used on the skin and must not come into contact with the eyes, nose, mouth, or vagina."
Answered by AI
What is butenafine hydrochloride cream used for?
"This medicine is for fungus infections of the skin. It can treat tinea (pityriasis) versicolor caused by M. furfur. The medicine works by either killing the fungus or preventing its growth. You need a prescription from a doctor to get this medicine."
Answered by AI
Can I use butenafine hydrochloride twice a day?
"You can use Mentax more than once or twice a day depending on what the package recommends or your doctor prescribes."
Answered by AI
Which is better clotrimazole or butenafine hydrochloride?
"Butenafine was more effective than clotrimazole in curing athletes foot, with 61.7% of those using butenafine being cured compared to 17.6% of those using clotrimazole."
Answered by AI