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What is Gastrografin
DiatrizoateThe Generic name of this drug
Treatment SummaryDiatrizoate is a type of x-ray contrast medium used to make organs or tissues appear clearer on an x-ray image. It is used for gastrointestinal studies, angiography (study of blood vessels) and urography (study of the urinary tract). It is available in two forms, diatrizoate meglumine and diatrizoate sodium.
Renografin-60is the brand name
Gastrografin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Renografin-60
Diatrizoate
1956
23
Approved as Treatment by the FDA
Diatrizoate, also known as Renografin-60, is approved by the FDA for 12 uses which include angiogram and computerized tomography .angiogram
computerized tomography
peripheral arteriography
splenoportography
Gastrointestinal and abdominal imaging procedures
Retrograde cystourethrography
Arteriography
excretory urography
Cholangiography
Arteriography
discography
selective coronary arteriography
Effectiveness
How Gastrografin Affects PatientsDiatrizoate is a type of drug that helps doctors diagnose medical conditions. It is made of iodine, which blocks x-rays, and when given to a patient it builds up in certain areas of the body. The x-ray film will show these areas as white, which helps doctors see if there are any special conditions in those areas.
How Gastrografin works in the bodyDiatrizoate is a type of X-ray contrast agent that contains iodine. The iodine makes the X-ray contrast more visible, so doctors can better see what's happening inside the body. It's a clear, colorless water solution that's safe to use almost anywhere in the body. It's often injected into a vein, but it can also be used in other areas like the spine, arteries, and abdomen.
When to interrupt dosage
The recommended dosage of Gastrografin is contingent upon the ascertained disorder, like Arteriography, angiogram and Gastrointestinal and abdominal imaging procedures. The dosage quantity varies as per the technique of administration recorded in the table below.Condition
Dosage
Administration
splenoportography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
peripheral arteriography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
selective coronary arteriography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
Arteriography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
hysterosalpingogram
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
excretory urography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
Retrograde cystourethrography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
Arteriography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
discography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
angiogram
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
Gastrointestinal and abdominal imaging procedures
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
computerized tomography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
Cholangiography
, 300.0 mg/mL, 180.0 mg/mL, 527.0 mg/mL, 50.0 %, 100.0 %, 30.0 %, 60.0 %, 18.0 %, 52.7 %, 66.0 %, 52.0 %, 660.0 mg/mL, 600.0 mg/mL, 760.0 mg/mL, 700.0 mg/mL, 76.0 %, 520.0 mg/mL, 0.6 mg/mg, 500.0 mg/mL, 0.9974 mg/mg
, Intravenous, Injection, solution, Injection, solution - Intravenous, Liquid, Oral; Rectal, Intrauterine, Injection, solution - Intrauterine, Intravesical, Injection, solution - Intravesical, Oral, Solution, Solution - Oral, Liquid - Intravenous, Powder, Powder - Oral, Liquid - Oral, Liquid - Oral; Rectal, Powder - Oral; Rectal, Intra-arterial; Intravenous, Liquid - Intra-arterial; Intravenous, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intravenous, Solution - Intra-arterial; Intravenous, Liquid - Intrauterine, Solution - Oral; Rectal, Powder, for solution, Powder, for solution - Oral, Intravascular, Injection, solution - Intravascular
Warnings
Gastrografin has eight contraindications and should not be employed in combination with the circumstances mentioned in the table below.Gastrografin ContraindicationsCondition
Risk Level
Notes
Carotid Arteries
Do Not Combine
Anuria
Do Not Combine
dehydrated azotemic patients
Do Not Combine
Sphenoid Sinusitis
Do Not Combine
direct injection into spinal arteries
Do Not Combine
Myelography
Do Not Combine
Structure of vertebral artery
Do Not Combine
use for examination of dorsal cysts
Do Not Combine
Common Gastrografin Drug Interactions
Drug Name
Risk Level
Description
Abacavir
Minor
Diatrizoate may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acetaminophen
Minor
Diatrizoate may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Aclidinium
Minor
Diatrizoate may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Diatrizoate may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Diatrizoate may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Gastrografin Toxicity & Overdose RiskDiatrizoate, a type of high-osmolality radiocontrast agent, can be toxic to kidney cells. The toxicity can lead to cell death, energy failure, changes in calcium levels, and disorganization of the cell structure. This toxicity is believed to be caused by oxidative stress.
Gastrografin Novel Uses: Which Conditions Have a Clinical Trial Featuring Gastrografin?
A single active clinical trial is currently being conducted to appraise the efficacy of Gastrografin in providing hysterosalpingogram, Arteriography and excretory urography for treatment of certain disorders.Condition
Clinical Trials
Trial Phases
hysterosalpingogram
0 Actively Recruiting
splenoportography
0 Actively Recruiting
Cholangiography
0 Actively Recruiting
Arteriography
0 Actively Recruiting
Arteriography
0 Actively Recruiting
selective coronary arteriography
0 Actively Recruiting
computerized tomography
1 Actively Recruiting
Not Applicable
Retrograde cystourethrography
0 Actively Recruiting
discography
0 Actively Recruiting
peripheral arteriography
0 Actively Recruiting
angiogram
0 Actively Recruiting
excretory urography
0 Actively Recruiting
Gastrointestinal and abdominal imaging procedures
0 Actively Recruiting
Gastrografin Reviews: What are patients saying about Gastrografin?
5Patient Review
1/2/2017 Even though this drink tastes like Nuclear Waste, it really helped the doctors locate my abscesses.
4.3Patient Review
11/22/2013 Even though the taste was really bad, I took Gastrografin as directed. Afterwards, I had lots of diarrhea that lasted for nine days. Is this normal?
3Patient Review
2/23/2017 I had to drink a litre of this stuff, which tasted like aniseed at first but quickly became unpalatable. I experienced some bloating and wind after drinking it, followed by stomach pain and diarrhea four hours later.
2Patient Review
6/17/2021 I took the first half at 7 am the day before the C T scan took the second half at 7 pm it started to work at 10 pm, My C T scan was 11am the next morning i got to the hospital and the bowel was still working they done the CT scan and when they had finished the scan the bowel started to work again what a mess, i got home and the bowel stop working at 4 p m. The hospital should tell to take Gastrografin two day's before there would not be a problem
1Patient Review
9/30/2014 This treatment successfully removed a small bowel obstruction that I was experiencing. However, the severe diarrhea that followed for the next 24 hours was quite unpleasant.
Patient Q&A Section about gastrografin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does Gastrografin make you poop?
"Gastrografin is a mild laxative. It will remove most stool, but it can also help us distinguish stool from polyps. The test may fail, and we may need to repeat it."
Answered by AI
What are side effects of Gastrografin?
"If you experience any of the following symptoms after taking medication, you may be experiencing an allergy: nausea, vomiting, diarrhea, hives and redness, low blood oxygen, shortness of breath, fast heart rate, and severe allergic reaction (anaphylaxis)."
Answered by AI
Is Gastrografin oral contrast?
"Gastrografin is a substance used to help radiologists see the gastrointestinal tract more clearly. It can be given orally or as an enema, and is usually only used when other substances (such as barium sulfate) can't be used."
Answered by AI
What is Gastrografin for small bowel obstruction?
"Gastrografin is a contrast medium that is commonly used to examine the gastrointestinal tract. The available evidence suggests that it can help predict and manage adhesional small bowel obstruction."
Answered by AI