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What is Noxivent
Nitric OxideThe Generic name of this drug
Treatment SummaryNitric oxide (NO) is a gas made of nitrogen and oxygen molecules. It is used by the body for signaling purposes and is essential for many industrial processes. It is also an air pollutant created by car engines and power plants. It should not be confused with nitrous oxide (N2O), an anesthetic, or nitrogen dioxide (NO2), another air pollutant. Nitric oxide is a free radical that reacts with ozone in the air to create nitrogen dioxide, which can be identified by its reddish-brown color.
INOmaxis the brand name
Noxivent Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
INOmax
Nitric Oxide
1999
7
Effectiveness
How Noxivent Affects PatientsPersistent pulmonary hypertension of the newborn (PPHN) is a condition caused by either a primary issue or one that is linked to other diseases such as pneumonia. This causes high pressure in the lungs which results in an imbalance of oxygen in the body. Nitric Oxide has been found to help improve oxygen levels in patients with PPHN by widening the blood vessels in the lungs and balancing out the oxygen levels in the body.
How Noxivent works in the bodyNitric oxide helps relax the muscles in your blood vessels, allowing them to widen. This increases blood flow and lowers blood pressure. When inhaled, nitric oxide helps widen your airways, making it easier to breathe.
When to interrupt dosage
The portion of Noxivent is reliant upon the identified condition. The quantity of dosage is contingent upon the technique of delivery, as outlined in the table below.Condition
Dosage
Administration
Pulmonary Hypertension
0.00098 mg/mL, , 0.005 mL/mL, 0.000123 mg/mL, 800.0 ppm, 100.0 ppm, 400.0 ppm, 0.01 %, 0.08 %, 0.1 mg/mL, 0.8 mg/mL, 11.157 mg/mL
, Respiratory (inhalation), Gas, Gas - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Liquid, Topical, Liquid - Topical
Respiratory Failure
0.00098 mg/mL, , 0.005 mL/mL, 0.000123 mg/mL, 800.0 ppm, 100.0 ppm, 400.0 ppm, 0.01 %, 0.08 %, 0.1 mg/mL, 0.8 mg/mL, 11.157 mg/mL
, Respiratory (inhalation), Gas, Gas - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Liquid, Topical, Liquid - Topical
Warnings
Noxivent has one contraindication, so it should not be administered when confronted with the conditions in the ensuing table.Noxivent ContraindicationsCondition
Risk Level
Notes
Cerebrospinal fluid shunts procedure
Do Not Combine
Common Noxivent Drug Interactions
Drug Name
Risk Level
Description
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Nitric Oxide.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Nitric Oxide.
Abacavir
Minor
Nitric Oxide may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acebutolol
Minor
The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Acebutolol.
Aclidinium
Minor
Nitric Oxide may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Noxivent Novel Uses: Which Conditions Have a Clinical Trial Featuring Noxivent?
22 active studies are presently in progress to ascertain the effectiveness of Noxivent for treating Respiratory Failure.Condition
Clinical Trials
Trial Phases
Pulmonary Hypertension
30 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 1, Early Phase 1
Respiratory Failure
0 Actively Recruiting
Noxivent Reviews: What are patients saying about Noxivent?
3.7Patient Review
10/13/20113Patient Review
9/14/2011Patient Q&A Section about noxivent
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the indication for nitric oxide?
"Nitric oxide is a medication used to manage and treat hypoxic respiratory failure or persistent pulmonary hypertension of the newborn (PPHN). It is classified as a miscellaneous respiratory agent."
Answered by AI
How much does nitric oxide cost?
"Inhaled nitric oxide therapy is very costly, with a direct cost of $100 per hour at the institution where the study was conducted. The annual cost of inhaled nitric oxide therapy at this institution was approximately $1.8 million."
Answered by AI