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What is Tri-Sprintec
NorgestimateThe Generic name of this drug
Treatment SummaryEthinylestradiol is a synthetic form of the hormone estrogen. It was developed in 1938 with the goal of creating a form of estrogen that was more easily absorbed by the body. It is commonly used in birth control pills and was approved by the FDA in 1943.
Ortho Tri Cyclenis the brand name
Tri-Sprintec Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ortho Tri Cyclen
Norgestimate
1989
113
Approved as Treatment by the FDA
Norgestimate, commonly known as Ortho Tri Cyclen, is approved by the FDA for 8 uses which include Oral Contraceptives and Osteoporosis, Postmenopausal .Oral Contraceptives
Used to treat Oral Contraceptives in combination with Ethinylestradiol
Osteoporosis, Postmenopausal
Used to treat Postmenopausal Osteoporosis in combination with Estradiol
Acne Vulgaris
Used to treat moderate Acne vulgaris in combination with Ethinylestradiol
moderate Vulvovaginal atrophy
Used to treat moderate Vulvovaginal atrophy in combination with Estradiol
Hot flashes
Used to treat Menopause in combination with Estradiol
moderate Menopausal Vasomotor Symptoms
Used to treat moderate Menopausal Vasomotor Symptoms in combination with Estradiol
Menopause
Used to treat severe Vasomotor Symptoms Associated With Menopause in combination with Estradiol
severe menopausal vulvovaginal atrophy
Used to treat severe menopausal vulvovaginal atrophy in combination with Estradiol
Effectiveness
How Tri-Sprintec Affects PatientsEthinylestradiol is a type of estrogen medication taken once a day. It helps to reduce luteinizing hormone and gonadotrophic hormones, which can stop ovulation and reduce the blood supply to the endometrium. It is generally considered safe with a low risk for side effects, however patients should be warned about potential risks of clotting.
How Tri-Sprintec works in the bodyEthinylestradiol is a synthetic estrogen. It is used in oral contraceptives to prevent pregnancy. It does this by suppressing ovulation, thickening cervical mucus, and blocking changes to the endometrium that would allow for fertilization. It also decreases luteinizing hormone, reducing the amount of blood vessels in the endometrium and increasing sex hormone binding globulin.
When to interrupt dosage
The measure of Tri-Sprintec is dependent upon the diagnosed circumstance, including Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. The amount of dosage is contingent upon the application procedure as elucidated in the table underneath.Condition
Dosage
Administration
Polycystic Ovarian Syndrome
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
moderate Vulvovaginal atrophy
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Menopause
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
severe menopausal vulvovaginal atrophy
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Osteoporosis, Postmenopausal
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Oral Contraceptives
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Menorrhagia
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Hirsutism
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
moderate Menopausal Vasomotor Symptoms
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Hot flashes
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Acne Vulgaris
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Dysmenorrhea
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Warnings
Tri-Sprintec has twenty-six contraventions, and should not be utilized when afflicting any of the conditions enumerated in the table beneath.Tri-Sprintec ContraindicationsCondition
Risk Level
Notes
Breast
Do Not Combine
Breast Cancer
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Hypersensitivity
Do Not Combine
Venous Thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Metrorrhagia
Do Not Combine
Liver Neoplasms
Do Not Combine
Common Tri-Sprintec Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Norgestimate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Norgestimate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Norgestimate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Norgestimate.
Astemizole
Major
The metabolism of Astemizole can be increased when combined with Norgestimate.
Tri-Sprintec Toxicity & Overdose RiskWomen who overdose on Yaz may have symptoms such as bleeding, nausea, vomiting, breast pain, abdominal discomfort, drowsiness, and fatigue. Treatment for an overdose should include monitoring potassium, sodium levels, and signs of acidosis, as well as providing supportive care.
Tri-Sprintec Novel Uses: Which Conditions Have a Clinical Trial Featuring Tri-Sprintec?
38 active studies are currently being conducted to determine the efficacy of Tri-Sprintec in providing Folate supplementation therapy, Premenstrual Dysphoric Disorder and Menopausal relief.Condition
Clinical Trials
Trial Phases
Dysmenorrhea
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Osteoporosis, Postmenopausal
0 Actively Recruiting
Oral Contraceptives
1 Actively Recruiting
Not Applicable
Menopause
0 Actively Recruiting
Polycystic Ovarian Syndrome
7 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1
moderate Menopausal Vasomotor Symptoms
0 Actively Recruiting
Hirsutism
0 Actively Recruiting
Hot flashes
14 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4
moderate Vulvovaginal atrophy
0 Actively Recruiting
Menorrhagia
0 Actively Recruiting
severe menopausal vulvovaginal atrophy
0 Actively Recruiting
Tri-Sprintec Reviews: What are patients saying about Tri-Sprintec?
5Patient Review
5/26/2022 I've only been taking Tri-Sprintec for two weeks, and I'm already really pleased with it. No significant side effects yet—just some breast tenderness. I was hesitant to try it after reading some of the negative reviews online, but I'm glad I did. It's affordable and works well, so I would definitely recommend it.
5Patient Review
7/15/2022 I had sex with my boyfriend and he came inside of me. I'm thankful that I was on this combination birth control, because my period started a week later. The only downside is that my period lasted for weeks, but I'm still grateful that there was no pregnancy.
4Patient Review
2/15/2022 Overall, this pill has been helpful in keeping me from getting pregnant and my period regular. However, the negative side effects can't be ignored. I've experienced moodiness, depression, headaches, and nausea while on this medication.
4Patient Review
12/1/2021 I started taking tri sprintec again last month and had awful flu-like symptoms for the first 1-2 weeks. After that, though, I felt great. I'm hoping it will help with my hormonal acne but so far haven't seen much improvement.
3.7Patient Review
1/4/2022 I began taking this medication after coming off an implant. This decision was the worst decision. The side effects were worse than the implant. I gained about 30 lbs in about 4 months while continuing to be super active as I have always been. Overall, I did not feel like myself. I did not suffer from any depression or mood changes, but the weight was too much for me.
3.3Patient Review
8/2/2021 I've been on this birth control for a while now, and it's made me put on a lot of weight. I'm also always in a bad mood, which is really tough to deal with. On the bright side, my period was regular until I tried skipping the sugar pill; now it's all over the place again.
3.3Patient Review
12/21/2020 I'm on my second pack of this birth control, and I think my body is still adjusting to it. I've been feeling bloated, have had some irregular spotting, and my breasts are tender. I'm hoping these side effects will go away soon.
3.3Patient Review
8/5/2022 I went to the hospital because of brown discharge. I didn't know what it was, and I bled a lot of the time. Now I have these crazy headaches. It also gave me a yeast infection. This is the worst treatment I've ever had.
3Patient Review
1/24/2022 Within a few months of taking this birth control, I stopped feeling emotions. I also got two yeast infections, which were both very painful experiences.
3Patient Review
9/24/2022 While this birth control did decrease my chances of getting pregnant, the negative impacts on my mental and physical health were not worth it. I gained a lot of weight, felt constantly bloated and terrible, experienced anxiety and depression, and developed cystic acne.
2.7Patient Review
4/12/2022 I took this medication for a full year as directed, but I still got pregnant.
2.3Patient Review
2/21/2022 I experienced some nasty side effects like headaches, gas, and breast tenderness. Plus, I felt really anxious for no reason.
2.3Patient Review
6/7/2022 I started taking this kind of birth control as recommended by my gynecologist, but just a few days in I started vomiting for three days straight. I went to see a doctor and they told me that the pill was making me sick. I've since changed to another brand of birth control in the hopes that it won't have any negative side effects. All I want is to have less painful periods and be protected from pregnancy.
2Patient Review
9/14/2022 This birth control almost killed me. It gave me AGEP (very rare allergic reaction). I’d suggest googling the effects of AGEP and seriously seeking another form of b/c. I went through the worst pain of my life and it took months to recover.
1Patient Review
12/27/2020 I started feeling numb and tingly all over my body yesterday, after only taking this pill for the first time. I'm also wondering if it could be a side effect from coming off my depo shot. If anyone has any answers or insights, please let me know.
Patient Q&A Section about tri-sprintec
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Tri-Sprintec a good birth control?
"The Tri-Sprintec is just as effective as any other birth control pill. If you use it perfectly, then it is 99.7% effective, but if you use it like a regular person, then it is only 93% effective."
Answered by AI
What does Tri-Sprintec do to your body?
"This medication contains a combination of 2 hormones, a progestin, and an estrogen, which are used to prevent pregnancy. In addition to preventing pregnancy, birth control pills may also make your periods more regular, decrease blood loss, and painful periods, decrease your risk of ovarian cysts, and also treat acne."
Answered by AI
What kind of birth control is Tri-Sprintec?
"Norgestimate is a synthetic progestin derived from 19-nor-testosterone.
The text is discussing Tri-Sprintec, a combination oral contraceptive containing the progestational compound norgestimate, and the estrogenic compound ethinyl estradiol. Norgestimate is a synthetic progestin derived from 19-nor-testosterone."
Answered by AI
Will Tri-Sprintec make me gain weight?
"If you research online, you'll mostly find that women complain about gaining weight from birth control pills, not losing it. Tri-Sprintec doesn't have any ingredients known to cause weight loss; but, you can still lose weight through diet and exercise while taking this pill."
Answered by AI