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Mineral Supplement

Magnesium Supplements for High Blood Pressure

N/A
Waitlist Available
Research Sponsored by Brigham and Women's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Total Mg intake from supplements of no more than 100 mg/day
Be older than 18 years old
Must not have
Unwillingness and/or inability to swallow 4 pills per day
History of type 1 or 2 diabetes
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years

Summary

This trial will test whether magnesium glycinate lowers blood pressure.

Who is the study for?
This trial is for adults with high blood pressure (systolic 120-149 mmHg or diastolic 80-94 mmHg) who are willing to keep their diet and supplement intake the same during the study. They must have a BMI under 35, not take more than 100 mg/day of magnesium supplements, and cannot be planning to move out of Boston within a year.
What is being tested?
The trial is testing if taking magnesium glycinate (480 mg/day) for three months can lower blood pressure. Participants will either receive this supplement or a placebo without knowing which one they're getting.
What are the potential side effects?
While not specified here, common side effects from magnesium supplements may include stomach upset, diarrhea, nausea, and vomiting. However, individual reactions can vary.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I take 100 mg or less of magnesium supplements daily.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I cannot or will not take 4 pills daily.
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I have a history of diabetes (type 1 or 2).
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I have not had any cancer, except for non-melanoma skin cancer, in the last 5 years.
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I have a history of inflammatory bowel disease.
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I have a history of kidney disease.
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I am not pregnant, nursing, or planning to become pregnant during treatment.
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I have had kidney failure in the past.
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I have a history of heart disease, including heart attack, stroke, or procedures to improve blood flow to my heart.
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I have had pancreatitis before.
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I am unable to sign a consent form.
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I have been on dialysis.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: magnesiumActive Control1 Intervention
magnesium glycinate supplement, 480 mg/day
Group II: placeboPlacebo Group1 Intervention
placebo supplement

Find a Location

Who is running the clinical trial?

Pure EncapsulationsIndustry Sponsor
1 Previous Clinical Trials
120 Total Patients Enrolled
Brigham and Women's HospitalLead Sponsor
1,666 Previous Clinical Trials
11,843,407 Total Patients Enrolled

Media Library

Magnesium Glycinate Supplement (Mineral Supplement) Clinical Trial Eligibility Overview. Trial Name: NCT03688503 — N/A
High Blood Pressure Research Study Groups: magnesium, placebo
High Blood Pressure Clinical Trial 2023: Magnesium Glycinate Supplement Highlights & Side Effects. Trial Name: NCT03688503 — N/A
Magnesium Glycinate Supplement (Mineral Supplement) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03688503 — N/A
~5 spots leftby Aug 2025
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