Magnesium Supplements for High Blood Pressure

Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Waitlist Available

Sponsor: Brigham and Women's Hospital

Trial Summary

What is the purpose of this trial?This double-blind, placebo-controlled randomized clinical trial will test whether a magnesium glycinate supplement (480 mg/day) taken for 12 weeks lowers blood pressure.

Eligibility Criteria

This trial is for adults with high blood pressure (systolic 120-149 mmHg or diastolic 80-94 mmHg) who are willing to keep their diet and supplement intake the same during the study. They must have a BMI under 35, not take more than 100 mg/day of magnesium supplements, and cannot be planning to move out of Boston within a year.

Inclusion Criteria

I take 100 mg or less of magnesium supplements daily.

Exclusion Criteria

I cannot or will not take 4 pills daily.

I have a history of diabetes (type 1 or 2).

I have not had any cancer, except for non-melanoma skin cancer, in the last 5 years.

I have a history of inflammatory bowel disease.

I have a history of kidney disease.

I am not pregnant, nursing, or planning to become pregnant during treatment.

I have had kidney failure in the past.

I have a history of heart disease, including heart attack, stroke, or procedures to improve blood flow to my heart.

I have had pancreatitis before.

I am unable to sign a consent form.

I have been on dialysis.

Treatment Details

The trial is testing if taking magnesium glycinate (480 mg/day) for three months can lower blood pressure. Participants will either receive this supplement or a placebo without knowing which one they're getting.

2Treatment groups

Active Control

Placebo Group

Group I: magnesiumActive Control1 Intervention

magnesium glycinate supplement, 480 mg/day

Group II: placeboPlacebo Group1 Intervention

placebo supplement

Magnesium Glycinate Supplement is already approved in United States, Canada, European Union for the following indications:

🇺🇸 Approved in United States as Magnesium Glycinate for: