Humanized 3F8 Bispecific Antibody for Osteosarcoma

Phase 1 & 2

Waitlist Available

Research Sponsored by Y-mAbs Therapeutics

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up days 1 through 28 in cycle 1

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing a new protein drug that helps the body's defense system find and destroy harmful cells. It is likely aimed at patients who need new treatment options, possibly those with certain types of cancer.

Eligible Conditions

Osteosarcoma
Neuroblastoma
Solid Tumor Cancers

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ days 1 through 28 in cycle 1

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~days 1 through 28 in cycle 1

This trial's timeline: 3 weeks for screening, Varies for treatment, and days 1 through 28 in cycle 1 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Dose Limiting Toxicities (DLTs) Phase I

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Hu3F8-BsAbExperimental Treatment2 Interventions

Phase I Hu3F8-BsAb is given IV over \~1-3 hours on Days 1 and 8 for each cycle. In cycle 1, blood is drawn for PK studies.Phase II Hu3F8-BsAb is given IV over \~1-3 hours on Days 1 and 8 for each cycle.

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