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PPOS group for Progestin-Ovarian Stimulation
Study Summary
This randomized trial aims to compare the euploid rate of blastocysts between PPOS and GnRH antagonist protocols in patients undergoing PGT-A. Infertile women who have medical indication for PGT-A will be recruited for study after explanation and counseling if they fulfill the inclusion criteria and do not have the exclusion criteria. Eligible women will be randomised into one of the two groups: Antagonist group: Women will receive antagonist once subcutaneously daily from day 6 of ovarian stimulation till the day of the ovulation trigger. PPOS group: Women will receive oral Duphaston 10mg bd from Day 3 till the day of ovulation trigger. The primary outcome is the euploidy rate of blastocysts.
- Euploidy
- Progestin-Ovarian Stimulation
- Preimplantation Genetic Testing
- Gonadotropin-Releasing Hormone Antagonist
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Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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