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Radiation Therapy

Radiosurgery Three Treatments for Brain Metastases (MIGRAINE Trial)

Phase 2
Waitlist Available
Led By Steven Chmura, MD
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 years
Awards & highlights
No Placebo-Only Group

Summary

This trial is comparing different ways to do surgery for brain cancer.

Eligible Conditions
  • Brain Metastases
  • Brain Tumor

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Multi-Fraction SRS superiority compared to single fraction SRS
Secondary study objectives
Acute CTCAE v5.0 CNS Grade 2+ and Grade 3+ toxicities
Late CTCAE v5.0 CNS Grade 2+ and Grade 3+ toxicities
Overall Survival Rate
+6 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Arm AExperimental Treatment1 Intervention
Group II: ARM BActive Control1 Intervention

Find a Location

Who is running the clinical trial?

University of ChicagoLead Sponsor
1,056 Previous Clinical Trials
760,783 Total Patients Enrolled
Steven Chmura, MDPrincipal InvestigatorUniversity of Chicago
4 Previous Clinical Trials
187 Total Patients Enrolled
~0 spots leftby Dec 2025
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