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HR20013 for Nausea and Vomiting Associated With Moderate Emetic Risk Anticancer Agents

Guangzhou, China
Phase 3
Recruiting
Research Sponsored by Fujian Shengdi Pharmaceutical Co., Ltd.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up the acute phase (0-24 hours), the delayed phase(24 - 120 hours), and the overall phase (0-120 hours) after initiation of moderate emetic risk anticancer agents, respectively
Awards & highlights
Pivotal Trial

Summary

This study is aimed to evaluate the efficacy and safety of HR20013 versus palonosetron for nausea and vomiting associated with moderate emetic risk anticancer agents

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Eligible Conditions
  • Chemotherapy-induced nausea and vomiting

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~the acute phase (0-24 hours), the delayed phase(24 - 120 hours), and the overall phase (0-120 hours) after initiation of moderate emetic risk anticancer agents, respectively
This trial's timeline: 3 weeks for screening, Varies for treatment, and the acute phase (0-24 hours), the delayed phase(24 - 120 hours), and the overall phase (0-120 hours) after initiation of moderate emetic risk anticancer agents, respectively for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Complete response rate in the delayed phase
Secondary study objectives
Adverse events
Complete response rate in the acute phase.
Complete response rate in the overall phase.
+8 more

Awards & Highlights

Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: HR20013 + dexamethasone + palonosetron placeboExperimental Treatment1 Intervention
Group II: Palonosetron + dexamethasone + HR20013 placeboActive Control1 Intervention

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Who is running the clinical trial?

Fujian Shengdi Pharmaceutical Co., Ltd.Lead Sponsor
35 Previous Clinical Trials
5,361 Total Patients Enrolled
~318 spots leftby Sep 2025