The Effect of Donepezil on Wound Healing
Palo Alto (17 mi)Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Phase 2
Recruiting
Sponsor: University of Maryland, Baltimore
Prior Safety Data
Approved in 4 jurisdictions
Trial Summary
What is the purpose of this trial?This trial tests if donepezil, a drug for Alzheimer's, can help heal difficult wounds in diabetic patients by improving blood flow and reducing swelling. Donepezil is already approved in many countries for treating Alzheimer's disease.
Eligibility Criteria
Treatment Details
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Donepezil and Topical Zinc OxideExperimental Treatment2 Interventions
donepezil 5mg daily and topical zinc oxide 20% three times daily
Group II: Placebo and Topical Zinc OxidePlacebo Group2 Interventions
Placebo daily and topical zinc oxide 20% three times daily
Donepezil is already approved in European Union, United States, Canada, Japan for the following indications:
🇪🇺 Approved in European Union as Aricept for:
- Alzheimer's disease
🇺🇸 Approved in United States as Aricept for:
- Alzheimer's disease
- Mild to moderate dementia of the Alzheimer's type
🇨🇦 Approved in Canada as Aricept for:
- Alzheimer's disease
🇯🇵 Approved in Japan as Aricept for:
- Alzheimer's disease
Find a clinic near you
Research locations nearbySelect from list below to view details:
University of Maryland Shore Medical Center at EastonEaston, MD
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Who is running the clinical trial?
University of Maryland, BaltimoreLead Sponsor